| 产品编号 | bs-17725R |
| 英文名称 | MOSC2 |
| 中文名称 | MOSC2蛋白抗体 |
| 别 名 | FLJ20605; mitochondrial; MOCO sulphurase C-terminal domain containing 2; MOSC domain-containing protein 2; MOSC2; MOSC2_HUMAN; RP11-270A6.1. |
| 研究领域 | 肿瘤 细胞生物 信号转导 新陈代谢 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Rat (predicted: Human,Mouse) |
| 产品应用 | WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, ICC=1:100-500, IF=1:100-500, ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 35kDa |
| 细胞定位 | 细胞浆 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human MOSC2: 101-200/335 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
MOSC2 is a 335 amino acid peripheral membrane protein that localizes to the mitochondria. Containing a MOSC domain, MOSC2 utilizes molybdenum as a cofactor and is a component of the benzamidoxime prodrug-converting complex that is comprised of cytochrome b5, NADH-cytochrome b5 reductase (CYB5R3). CYB5R3 belongs to the flavoprotein pyridine nucleotide cytochrome reductase family and is involved in the desaturation and elongation of fatty acids, cholesterol biosynthesis, drug metabolism and, in erythrocytes, methemoglobin reduction. Benzamidoxime prodrug-converting complex is required to reduce N-hydroxylated structures, such as benzamidoxime prodrug. MOSC2 exists as two alternatively spliced isoforms and is encoded by a gene mapping to human chromosome 1q41. Function: Catalytic component of the benzamidoxime prodrug-converting complex, a complex required to reduce N-hydroxylated structures, such as benzamidoxime prodrug. Benzamidoxime is an amidine prodrug produced by N-hydroxylation which is used to enhance bioavailability and increase intestinal absorption. It is then reduced into benzamidine, its active amidine, by the benzamidoxime prodrug-converting complex. Subcellular Location: Mitochondrion outer membrane. Similarity: Contains 1 MOSC domain. SWISS: Q969Z3 Gene ID: 54996 Database links: Entrez Gene: 54996 Human Entrez Gene: 67247 Mouse SwissProt: Q969Z3 Human SwissProt: Q922Q1 Mouse Unigene: 369042 Human Unigene: 177724 Mouse |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
