| 产品编号 | bs-18090R |
| 英文名称 | Rabbit Anti-HSPC210/GSK3beta interaction protein antibody |
| 中文名称 | GSK3β相互作用蛋白抗体 |
| 别 名 | C14ORF129; Chromosome 14 open reading frame 129; GSK3-beta interaction protein; GSK3beta interaction protein; GSKIP; GSKIP; GSKIP_HUMAN; MGC4945; UPF0279. |
| 研究领域 | 细胞生物 免疫学 信号转导 细胞周期蛋白 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | (predicted: Human,Mouse,Rat,Cynomolgus Monkey) |
| 产品应用 | IHC-P=1:100-500,IHC-F=1:100-500,ICC=1:100-500,IF=1:100-500
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 16kDa |
| 细胞定位 | 细胞浆 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human GSKIP : 1-100/139 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
This gene encodes a protein that is involved as a negative regulator of GSK3-beta in the Wnt signaling pathway. The encoded protein may play a role in the retinoic acid signaling pathway by regulating the functional interactions between GSK3-beta, beta-catenin and cyclin D1, and it regulates the beta-catenin/N-cadherin pool. The encoded protein contains a GSK3-beta interacting domain (GID) in its C-terminus, which is similar to the GID of Axin. The protein also contains an evolutionarily conserved RII-binding domain, which facilitates binding with protein kinase-A and GSK3-beta, enabling its role as an A-kinase anchoring protein. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Dec 2012] Subcellular Location: Cytoplasm. Tissue Specificity: Detected in heart, brain, placenta, liver, skeletal muscle, kidney, testis, lung and pancreas. Similarity: Belongs to the UPF0279 family. SWISS: Q9P0R6 Gene ID: 51527 Database links: Entrez Gene: 51527 Human Entrez Gene: 66787 Mouse SwissProt: Q9P0R6 Human SwissProt: Q8BGR8 Mouse Unigene: 728153 Human Unigene: 248019 Mouse Unigene: 3701 Rat |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
