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HYLS1 Rabbit pAb (bs-18114R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价

产品编号 bs-18114R
英文名称 HYLS1 Rabbit pAb
中文名称 Hydrolethalus综合征蛋白1抗体
别    名 HLS; Hydrolethalus syndrome protein 1; HYLS1; HYLS1_HUMAN.  
研究领域 细胞生物  发育生物学  神经生物学  
抗体来源 Rabbit
克隆类型 Polyclonal
克 隆 号
交叉反应 Mouse,Rat (predicted: Human,Rabbit,Cow)
产品应用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 34 kDa
检测分子量
细胞定位 细胞浆 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human HYLS1: 51-150/299 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 This gene encodes a protein localized to the cytoplasm. Mutations in this gene are associated with hydrolethalus syndrome. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Oct 2008]

Subcellular Location:
Cytoplasm.

DISEASE:
Defects in HYLS1 are the cause of hydrolethalus syndrome type 1 (HLS1) [MIM:236680]. HLS1 is a lethal malformation syndrome leading to stillbirth or death shortly after birth. It is characterized by hydrocephaly with absent upper midline structures of the brain, micrognathia and polydactyly.

Similarity:
Belongs to the HYLS1 family.

SWISS:
Q96M11

Gene ID:
219844

Database links:

Entrez Gene: 219844 Human

Omim: 610693 Human

SwissProt: Q96M11 Human

Unigene: 585071 Human



产品图片
Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (HYLS1) Polyclonal Antibody, Unconjugated (bs-18114R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
Paraformaldehyde-fixed, paraffin embedded (Rat brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (HYLS1) Polyclonal Antibody, Unconjugated (bs-18114R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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