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TNPO3 Rabbit pAb (bs-18158R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价
产品编号 bs-18158R
英文名称 TNPO3 Rabbit pAb
中文名称 转运蛋白3抗体
别    名 TNPO 3; Imp12; Importin 12; Importin-12; IPO12; MTR10A; TNPO 3; TNPO3; TNPO3_HUMAN; Transportin 3; Transportin SR; Transportin-3; Transportin-SR; TRN SR; TRN-SR; TRN-SR2; TRNSR.  
研究领域 细胞生物  免疫学  信号转导  转录调节因子  脂蛋白  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human,Mouse,Rat,Sheep,Cow,Horse)
产品应用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 104 kDa
检测分子量
细胞定位 细胞核 细胞浆 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human TNPO3: 821-923/923 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 The protein encoded by this gene is a nuclear import receptor for serine/arginine-rich (SR) proteins such as the splicing factors SFRS1 and SFRS2. The encoded protein has also been shown to be involved in HIV-1 infection, apparently through interaction with the HIV-1 capsid protein. Two transcript variants encoding different isoforms as well as a noncoding transcript have been found for this gene.[provided by RefSeq, Jul 2010]

Function:
Seems to function in nuclear protein import as nuclear transport receptor. In vitro, mediates the nuclear import of splicing factor SR proteins SFRS1 and SFRS2, by recognizing phosphorylated RS domains.

Subunit:
Interacts with phosphorylated SFRS1 and SFRS2. Interacts with NUP62 and RBM4.

Subcellular Location:
Cytoplasm. Nucleus.

SWISS:
Q9Y5L0

Gene ID:
23534

Database links:

Entrez Gene: 23534 Human

Entrez Gene: 320938 Mouse

Omim: 610032 Human

SwissProt: Q9Y5L0 Human

SwissProt: Q6P2B1 Mouse

Unigene: 193613 Human

Unigene: 276381 Mouse

Unigene: 304472 Mouse

Unigene: 352219 Mouse

Unigene: 424508 Mouse

Unigene: 429470 Mouse

Unigene: 439108 Mouse



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