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Rabbit Anti-LY6H  antibody (bs-18455R)
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价
产品编号 bs-18455R
英文名称 LY6H
中文名称 淋巴细胞抗原6H抗体
别    名 Ly-6H; LY 6H; Lymphocyte antigen 6 complex locus H; Lymphocyte antigen 6H; NMLY 6; NMLY6.  
研究领域 细胞生物  免疫学  淋巴细胞  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human,Mouse,Rat,Pig,Cow,Horse,Sheep)
产品应用 IHC-P=1:100-500, IHC-F=1:100-500, ICC=1:100-500, IF=1:100-500, ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 12kDa
细胞定位 细胞膜 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human LY6H: 21-100/140 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 The Ly-6 (Lymphocyte antigen 6) alloantigens represent a family of phosphatidylinositol-anchored proteins that play a role in the process of T lymphocyte activation. Ly-6 family members share amino acid homology throughout a distinctive cysteine rich protein domain that incorporates O-linked carbohydrates. During hematopoiesis, murine Ly-6 molecules have unique patterns of tissue expression, from multipotential stem cells to lineage committed precursor cells, and on specific leukocyte subpopulations in the peripheral lymphoid tissues. Ly-6H (Lymphocyte antigen 6H), also known as NMLY6, is a 140 amino acid lipid-anchored membrane protein that belongs to the Ly-6 family. Highly expressed in brain with lower expression in pancreas, testis, colon and small intestine, Ly-6H participates in the activation of T lymphocytes. Overexpression of Ly-6H is detected in certain acute human leukemic cell lines (such as MOLT-3), suggesting a possible role for Ly-6H in carcinogenesis.

Subcellular Location:
Cell membrane. Lipid-anchor, GPI-anchor.

Tissue Specificity:
Highly expressed in brain (cerebral cortex, amygdala, hippocampus and subthalamic nucleus) and in acute human leukemic cell line MOLT-3. Also found in lower levels in testis, pancreas, small intestine and colon.

SWISS:
O94772

Gene ID:
4062

Database links:

Entrez Gene: 4062 Human

Omim: 603625 Human

SwissProt: O94772 Human

Unigene: 159590 Human



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