| 产品编号 | bs-18521R |
| 英文名称 | ZFAT/ZNF406 |
| 中文名称 | 锌指蛋白406抗体 |
| 别 名 | AITD3; KIAA1485; MGC126815; MGC126817; ZFAT; ZFAT zinc finger 1; ZFAT_HUMAN; ZFAT1; zinc finger and AT hook domain containing; Zinc finger gene in AITD susceptibility region; zinc finger gene in autoimmune thyroid disease; Zinc finger protein 406; Zinc finger protein ZFAT; ZNF406; |
| 研究领域 | 细胞生物 免疫学 淋巴细胞 t-淋巴细胞 b-淋巴细胞 表观遗传学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | (predicted: Human,Mouse,Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep) |
| 产品应用 | IHC-P=1:100-500, IHC-F=1:100-500, ICC=1:100-500, IF=1:100-500
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 139kDa |
| 细胞定位 | 细胞核 细胞浆 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human ZFAT/ZNF406: 961-1060/1243 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
This gene encodes a protein that likely binds DNA and functions as a transcriptional regulator involved in apoptosis and cell survival. This gene resides in a susceptibility locus for autoimmune thyroid disease (AITD) on chromosome 8q24. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Nov 2009] Function: May be involved in transcriptional regulation. Overexpression causes down-regulation of a number of genes involved in the immune response. Some genes are also up-regulated. Subcellular Location: Nucleus. Cytoplasm > cytosol. Tissue Specificity: Isoform 1 is strongly expressed in placenta, spleen, kidney, testis and peripheral blood leukocytes. Expressed in CD4+ and CD8+ T-cells, CD19+ B-cells and CB14+ monocytes. Isoform 3 is strongly expressed in placenta, ovary, tonsil, CD19+ B-cells and CD14+ monocytes. Similarity: Contains 19 C2H2-type zinc fingers. SWISS: Q9P243 Gene ID: 57623 Database links: Entrez Gene: 57623 Human Entrez Gene: 380993 Mouse Omim: 610931 Human SwissProt: Q9P243 Human SwissProt: Q7TS63 Mouse Unigene: 446172 Human Unigene: 309526 Mouse Unigene: 33031 Rat |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
