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Rabbit Anti-Mannosidase II  antibody (bs-18655R)
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价
产品编号 bs-18655R
英文名称 Mannosidase II
中文名称 α-甘露糖苷酶2抗体
别    名 3-1; 6-alpha-mannosidase; Alpha mannosidase 2; alpha Mannosidase II; alpha Mannosidase II; Alpha-mannosidase 2; AMAN II; Golgi alpha mannosidase II; Golgi alpha-mannosidase II; Golgi integral membrane protein 7; GOLIM7; MA2A1_HUMAN; MAN II; MAN2A1; MANA 2; MANA2; MANII; Mann II; Mann II; Mannosidase alpha class 2A member 1; Mannosidase Two; Mannosidase Two; Mannosidase, alpha type II; Mannosidase, alpha, II; Mannosyl oligosaccharide 1 3 1 6 alpha mannosidase; Mannosyl oligosaccharide 1,3 1,6 alpha mannosidase; Mannosyl oligosaccharide 13 16 alpha mannosidase; Mannosyl-oligosaccharide 1.  
研究领域 肿瘤  细胞生物  免疫学  信号转导  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human,Mouse,Rat)
产品应用 IHC-P=1:100-500, IHC-F=1:100-500, ICC=1:100-500, IF=1:100-500, ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 131kDa
细胞定位 细胞膜 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Mannosidase II: 351-450/1144 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 This gene encodes a glycosyl hydrolase that localizes to the Golgi and catalyzes the final hydrolytic step in the asparagine-linked oligosaccharide (N-glycan) maturation pathway. Mutations in the mouse homolog of this gene have been shown to cause a systemic autoimmune disease similar to human systemic lupus erythematosus. [provided by RefSeq, Dec 2013]

Function:
Catalyzes the first committed step in the biosynthesis of complex N-glycans. It controls conversion of high mannose to complex N-glycans; the final hydrolytic step in the N-glycan maturation pathway.

Subunit:
Homodimer; disulfide-linked

Subcellular Location:
Golgi apparatus membrane; Single-pass type II membrane protein

Similarity:
Belongs to the glycosyl hydrolase 38 family.

SWISS:
Q16706

Gene ID:
4124

Database links:

Entrez Gene: 4124 Human

Omim: 154582 Human

SwissProt: Q16706 Human

Unigene: 432822 Human



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