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Rabbit Anti-STAC  antibody (bs-10761R)
~~~促销,代码KX240301~~~
~~~促销,代码KX240302~~~
订购热线:400-901-9800
订购邮箱:sales@bioss.com.cn
订购QQ:  400-901-9800
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价
产品编号 bs-10761R
英文名称 STAC
中文名称 STAC1蛋白抗体
别    名 SH3 and cysteine rich domain; SH3 and cysteine rich domain containing protein; SRC homology 3 and cysteine rich domain protein; Src homology three (SH3) and cysteine rich domain; STAC 1; STAC1; STAC-1; FLJ32331; STAC_HUMAN.  
研究领域 神经生物学  信号转导  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human,Mouse,Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep)
产品应用 IHC-P=1:100-500, IHC-F=1:100-500, ICC=1:100-500, IF=1:100-500, ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 45kDa
细胞定位 细胞浆 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human STAC: 21-120/402 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 STAC is a 402 amino acid protein that contains one SH3 (Src homology 3) domain and one cysteine-rich domain (CRD). Expressed in brain, STAC is a neuron-specific protein that localizes to the cytoplasm and, based on the frequent involvement of SH3 and CRD domains in signal transduction, is believed to play a role in neuron-specific signal transduction. In addition, STAC may be involved in protecting cells from apoptosis. Due to its neuron-specific expression and putative role in signal transduction, STAC may be implicated in a variety of hereditary neurological diseases.

Function:
Probably involved in a neuron-specific signal transduction.

Subcellular Location:
Cytoplasmic.

Similarity:
Contains 1 phorbol-ester/DAG-type zinc finger.
Contains 1 SH3 domain.

SWISS:
Q99469

Gene ID:
6769

Database links:

Entrez Gene: 6769 Human

Entrez Gene: 20840 Mouse

Entrez Gene: 363152 Rat

Omim: 602317 Human

SwissProt: Q99469 Human

SwissProt: P97306 Mouse

Unigene: 56045 Human

Unigene: 1414 Mouse



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