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Rabbit Anti-MED12L  antibody (bs-18792R)
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价
产品编号 bs-18792R
英文名称 MED12L
中文名称 甲状腺激素受体相关蛋白复合物230样蛋白抗体
别    名 MD12L_HUMAN; MED12L; Mediator complex subunit 12-like protein; Mediator of RNA polymerase II transcription subunit 12-like protein; NOPAR; Thyroid hormone receptor-associated-like protein; TNRC11L; TRALP; TRALPUSH; Trinucleotide repeat-containing gene 11 protein-like.  
研究领域 细胞生物  转录调节因子  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human)
产品应用 IHC-P=1:100-500, IHC-F=1:100-500, ICC=1:100-500, IF=1:100-500, ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 240kDa
细胞定位 细胞核 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human MED12L: 601-700/2145 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 The protein encoded by this gene is part of the Mediator complex, which is involved in transcriptional coactivation of nearly all RNA polymerase II-dependent genes. The Mediator complex links gene-specific transcriptional activators with the basal transcription machinery. [provided by RefSeq, May 2010]

Function:
May be a component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.

Subunit:
Belongs to the Mediator complex subunit 12 family.

Subcellular Location:
Nucleus.

Similarity:
Belongs to the Mediator complex subunit 12 family.

SWISS:
Q86YW9

Gene ID:
116931

Database links:

Entrez Gene: 116931 Human

Omim: 611318 Human

SwissProt: Q86YW9 Human

Unigene: 58561 Human

Unigene: 730822 Human



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