| 产品编号 | bs-18904R |
| 英文名称 | MFSD6 |
| 中文名称 | MFSD6蛋白抗体 |
| 别 名 | FLJ20160; HMMR2; macrophage MHC class I receptor 2 homolog; Macrophage MHC class I receptor 2 homolog; Macrophage MHC receptor 2; Major facilitator superfamily domain containing protein 6; MFSD6; MMR2; OTTHUMP00000163510; OTTHUMP00000205546; OTTHUMP00000205548. |
| 研究领域 | 肿瘤 免疫学 信号转导 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | (predicted: Human,Mouse,Rat,Dog,Pig,Cow,Horse,Sheep) |
| 产品应用 | IHC-P=1:100-500, IHC-F=1:100-500, ICC=1:100-500, IF=1:100-500
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 88kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human MFSD6: 621-720/791 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
MFSD6L is a 586 amino acid multi-pass membrane protein of the MFSD6 family and major facilitator superfamily. The gene encoding MFSD6L maps to human chromosome 17, which contains about 81 million bases and 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, though it is specifically recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes. Chromosome 17 is also linked to neurofibromatosis, a condition characterized by neural and epidermal lesions, and dysregulated Schwann cell growth. Subunit: May interact with HLA-B62. Subcellular Location: Membrane Tissue Specificity: Widely expressed. Expression levels in peripheral blood mononuclear cells are highly variable between individuals, including no expression at all. Similarity: Belongs to the major facilitator superfamily. MFSD6 family. SWISS: Q6ZSS7 Gene ID: 54842 Database links: Entrez Gene: 54842 Human Omim: 613476 Human SwissProt: Q6ZSS7 Human |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
