| 产品编号 | bs-18909R |
| 英文名称 | MGAT4C |
| 中文名称 | MGAT4C蛋白抗体 |
| 别 名 | 3-D-mannoside beta-1; 3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C; 4-N-acetylglucosaminyltransferase IVc; Alpha-1; GlcNAc-T IVc; GnT-IVc; hGnT-IV-H; MGAT4C; MGT4C_HUMAN; N-acetylglucosaminyltransferase IV homolog; N-acetylglucosaminyltransferase IVc; N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVc; UDP-N-acetylglucosamine: alpha-1. |
| 研究领域 | 肿瘤 细胞生物 免疫学 信号转导 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | (predicted: Human,Mouse,Rat) |
| 产品应用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 56kDa |
| 细胞定位 | 细胞浆 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human MGAT4C: 351-450/478 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
MGAT4C is a 478 amino acid single-pass type II membrane protein that localizes to the golgi apparatus and belongs to the glycosyltransferase 54 family. Expressed in liver, heart, testis, brain and adrenal gland, GnT-IVH functions as a glycosyltransferase that catalyzes the transfer of N-acetylglucosamine (GlcNAc) to the core mannose residues of N-linked glycans, thereby playing a crucial role in the production of tri- and tetra-antennary N-linked sugar chains. The gene encoding GnT-IVH maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome. Function: Glycosyltransferase that participates in the transfer of N-acetylglucosamine (GlcNAc) to the core mannose residues of N-linked glycans. Catalyzes the formation of the GlcNAcbeta1-4 branch on the GlcNAcbeta1-2Manalpha1-3 arm of the core structure of N-linked glycans. Essential for the production of tri- and tetra-antennary N-linked sugar chains (By similarity). Does not catalyze the transfer of GlcNAc to the Manalpha1-6 arm to form GlcNAcBeta1-4Manalpha1-6 linkage ('GnT-VI' activity). Subcellular Location: Golgi apparatus membrane. Tissue Specificity: Expressed in heart, adrenal gland, testis, liver, brain and fetal brain. Not expressed in pancreas. Similarity: Belongs to the glycosyltransferase 54 family. SWISS: Q9UBM8 Gene ID: 25834 Database links: Entrez Gene: 25834 Human SwissProt: Q9UBM8 Human Unigene: 589093 Human |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
