| 产品编号 | bs-18947R |
| 英文名称 | MITD1 |
| 中文名称 | MITD1蛋白抗体 |
| 别 名 | Microtubule interacting and transport domain containing 1; MIT; MIT domain containing protein 1; MIT microtubule interacting and transport domain containing 1; MITD 1. |
| 研究领域 | 细胞生物 免疫学 信号转导 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | (predicted: Human,Mouse,Rat,Chicken,Pig,Cow,Horse,Rabbit,Sheep) |
| 产品应用 | IHC-P=1:100-500, IHC-F=1:100-500, ICC=1:100-500, IF=1:100-500
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 29kDa |
| 细胞定位 | 细胞浆 细胞膜 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human MITD1: 141-240/249 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
MITD1 is a 249 amino acid peripheral membrane protein that localizes to the cytoplasmic side of late endosomes, where it is Implicated in endosomal protein transport. MITD1 interacts with CHMP2 and CHMP1B, and is encoded by a gene that maps to human chromosome 2q11.2. As the second largest human chromosome, chromosome 2 consists of 237 million bases, encodes over 1,400 genes and makes up approximately 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstr鰉 syndrome is due to mutations in the ALMS1 gene. Function: Required for efficient abscission at the end of cytokinesis, together with components of the ESCRT-III complex. Subunit: Homodimer. Interacts (via MIT domain) with CHMP1A, CHMP1B, CHMP2A and IST1. Subcellular Location: Late endosome membrane; Peripheral membrane protein; Cytoplasmic side. Midbody. Membrane; Peripheral membrane protein; Cytoplasmic side. Similarity: Contains 1 MIT domain. SWISS: Q8WV92 Gene ID: 129531 Database links: Entrez Gene: 129531 Human Entrez Gene: 69028 Mouse SwissProt: Q8WV92 Human SwissProt: Q8VDV8 Mouse |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
