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Rabbit Anti-NAALADL2  antibody (bs-18993R)
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价
产品编号 bs-18993R
英文名称 NAALADL2
中文名称 NAALADL2蛋白抗体
别    名 Glutamate carboxypeptidase II type non peptidase homologue; Inactive N acetylated alpha linked acidic dipeptidase like protein 2; Inactive N-acetylated-alpha-linked acidic dipeptidase-like protein 2; N acetylated alpha linked acidic dipeptidase like 2; NAALADase L2; NAALADL 2; NAALADL2; NADL2_HUMAN.  
研究领域 细胞生物  免疫学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human,Mouse,Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit,Zebrafish,GuineaPig,Cat,Saccharomyces cerevisiae)
产品应用 WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, ICC=1:100-500, IF=1:100-500, ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 38kDa
细胞定位 细胞膜 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human NAALADL2: 21-120/795 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 NAALADL2 is a 795 amino acid single-pass type II membrane protein that belongs to the peptidase M28 family and M28B subfamily. Existing as two alternatively spliced isoforms, NAALADL2 is expressed at highest levels in placenta and kidney, and has also been observed in certain embryonic tissues. NAALADL2 may be catalytically inactive. The gene encoding NAALADL2 maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Key tumor suppressing genes on chromosome 3 include those that encode the apoptosis mediator RASSF1, the cell migration regulator HYAL1 and the angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3.

Function:
May be catalytically inactive.

Subcellular Location:
Membrane.

Tissue Specificity:
Expressed at higher level in kidney and placenta. In embryo, it is mainly confined to duodenal and stomach endoderm, mesonephros, metanephros and pancreas.

Similarity:
Belongs to the peptidase M28 family. M28B subfamily.

SWISS:
Q58DX5

Gene ID:
254827

Database links:

Entrez Gene: 254827 Human

Entrez Gene: 635702 Mouse

Entrez Gene: 499583 Rat

Omim: 608806 Human

SwissProt: Q58DX5 Human

Unigene: 565848 Human

Unigene: 603646 Human

Unigene: 660010 Human

Unigene: 448351 Mouse



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