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Rabbit Anti-NANS  antibody (bs-19009R)
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价
产品编号 bs-19009R
英文名称 NANS
中文名称 N-乙酰神经氨酸合酶抗体
别    名 EC 2.5.1.56; EC 2.5.1.57; N acetylneuraminate 9 phosphate synthase; N acetylneuraminate synthase; N acetylneuraminic acid phosphate synthase; N acetylneuraminic acid synthase; N-acetylneuraminate synthase; N-acetylneuraminate-9-phosphate synthase; N-acetylneuraminic acid phosphate synthase; N-acetylneuraminic acid synthase; NANS; OTTHUMP00000021769; SAS; Sialic acid phosphate synthase; Sialic acid synthase; SIAS_HUMAN.  
研究领域 肿瘤  细胞生物  神经生物学  信号转导  新陈代谢  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human,Mouse,Rat,Chicken,Dog,Pig,Cow,Rabbit,Sheep)
产品应用 IHC-P=1:100-500, IHC-F=1:100-500, ICC=1:100-500, IF=1:100-500, ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 40kDa
细胞定位 细胞浆 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human NANS: 1-100/359 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 This gene encodes an enzyme that functions in the biosynthetic pathways of sialic acids. In vitro, the encoded protein uses N-acetylmannosamine 6-phosphate and mannose 6-phosphate as substrates to generate phosphorylated forms of N-acetylneuraminic acid (Neu5Ac) and 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN), respectively; however, it exhibits much higher activity toward the Neu5Ac phosphate product. In insect cells, expression of this gene results in Neu5Ac and KDN production. This gene is related to the E. coli sialic acid synthase gene neuB, and it can partially restore sialic acid synthase activity in an E. coli neuB-negative mutant. [provided by RefSeq, Jul 2008]

Function:
Produces N-acetylneuraminic acid (Neu5Ac) and 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN). Can also use N-acetylmannosamine 6-phosphate and mannose 6-phosphate as substrates to generate phosphorylated forms of Neu5Ac and KDN, respectively.

Tissue Specificity:
Ubiquitous.

Similarity:
Contains 1 AFP-like domain.

SWISS:
Q9NR45

Gene ID:
54187

Database links:

Entrez Gene: 540602 Cow

Entrez Gene: 54187 Human

Entrez Gene: 94181 Mouse

Entrez Gene: 298071 Rat

Omim: 605202 Human

SwissProt: Q9NR45 Human

Unigene: 522310 Human

Unigene: 665191 Human



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