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Rabbit Anti-NDST2  antibody (bs-19063R)
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价
产品编号 bs-19063R
英文名称 NDST2
中文名称 NDST2蛋白抗体
别    名 [Heparan sulfate]-glucosamine N-sulfotransferase; bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2; Glucosaminyl N-deacetylase/N-sulfotransferase 2; glucosaminyl N-deacetylase/N-sulphotransferase 2; heparan glucosaminyl N-deacetylase/N-sulfotransferase 2; heparan N-sulfotransferase 2; heparan sulfate N-deacetylase/N-sulfotransferase 2; Heparan sulfate N-sulfotransferase 2; HSST2; mastocytoma N-deacetylase/N-sulfotransferase; Mndns; N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2; N-heparan sulfate sulfotransferase 2; N-HSST 2; NDST-2; NDST2; NDST2_HUMAN; NST2.  
研究领域 细胞生物  免疫学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human,Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit,Cat)
产品应用 IHC-P=1:100-500, IHC-F=1:100-500, ICC=1:100-500, IF=1:100-500, ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 101kDa
细胞定位 细胞浆 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human NDST2: 1-100/883 <Cytoplasmic>
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 This gene encodes a member of the N-deacetylase/N-sulfotransferase subfamily of the sulfotransferase 1 proteins. The encoded enzyme has dual functions in processing glucosamine and heparin polymers, including N-deacetylation and N-sulfation. The encoded protein may be localized to the Golgi. [provided by RefSeq, Feb 2009]

Function:
Essential bifunctional enzyme that catalyzes both the N-deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. Modifies the GlcNAc-GlcA disaccharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. Plays a role in determining the extent and pattern of sulfation of heparan sulfate.

Subcellular Location:
Golgi apparatus membrane.

Similarity:
Belongs to the sulfotransferase 1 family. NDST subfamily.

SWISS:
P52849

Gene ID:
8509

Database links:

Entrez Gene: 286838 Cow

Entrez Gene: 489049 Dog

Entrez Gene: 100725589 Guinea pig

Entrez Gene: 100064113 Horse

Entrez Gene: 8509 Human

Entrez Gene: 17423 Mouse

Entrez Gene: 100151795 Pig

Entrez Gene: 100357859 Rabbit

Entrez Gene: 114002 Rat

Entrez Gene: 798226 Zebrafish

Omim: 603268 Human

SwissProt: O97583 Cow

SwissProt: P52849 Human

SwissProt: P52850 Mouse

Unigene: 654758 Human

Unigene: 4084 Mouse

Unigene: 7781 Rat



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