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Rabbit Anti-Multimerin 2  antibody (bs-19097R)

~~~促销,代码KT240603~~~
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价
产品编号 bs-19097R
英文名称 Rabbit Anti-Multimerin 2  antibody
中文名称 Multimerin 2蛋白抗体
别    名 Elastin microfibril interface located protein 3; Elastin microfibril interfacer 3; EMILIN like protein EndoGlyx 1; EMILIN-3; EMILIN3; ENDOGLYX 1; EndoGlyx-1; EndoGlyx-1 p125/p140 subunit; ENDOGLYX1; MMRN2; MMRN2_HUMAN; Multimerin-2.  
研究领域 细胞生物  细胞膜蛋白  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human,Mouse,Rat,Dog,Horse)
产品应用 IHC-P=1:100-500,IHC-F=1:100-500,ICC=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 102kDa
细胞定位 分泌型蛋白 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Multimerin 2: 361-460/949 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 This gene encodes a protein belonging to the member of elastin microfibril interface-located (EMILIN) protein family. This family member is an extracellular matrix glycoprotein that can interfere with tumor angiogenesis and growth. It serves as a transforming growth factor beta antagonist and can interfere with the VEGF-A/VEGFR2 pathway. A related pseudogene has been identified on chromosome 6. [provided by RefSeq, Aug 2012]

Function:
Inhibits endothelial cells motility and acts as a negative regulator of angiogenesis; it downregulates KDR activation by binding VEGFA.

Subcellular Location:
Secreted > extracellular space > extracellular matrix.

Tissue Specificity:
Endothelium.

Post-translational modifications:
N- and O-glycosylated.

Similarity:
Contains 1 C1q domain.
Contains 1 EMI domain.

SWISS:
Q9H8L6

Gene ID:
79812

Database links:

Entrez Gene: 79812 Human

Omim: 608925 Human

SwissProt: Q9H8L6 Human

Unigene: 524479 Human



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