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Rabbit Anti-PERP/p53 apoptosis effector related to PMP22  antibody (bs-10783R)
~~~促销,代码KX240301~~~
~~~促销,代码KX240302~~~
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价
产品编号 bs-10783R
英文名称 PERP/p53 apoptosis effector related to PMP22
中文名称 p53凋亡相关作用蛋白PMP22抗体
别    名 KCP 1; KCP-1; KCP1; Keratinocyte associated protein 1; Keratinocyte-associated protein 1; Keratinocytes associated protein 1; KRTCAP 1; KRTCAP1; p53 apoptosis effector related to PMP 22; p53 apoptosis effector related to PMP-22; p53 apoptosis effector related to PMP22; P53 induced protein PIGPC1; P53-induced protein PIGPC1; Perp; PERP TP53 apoptosis effector; PERP_HUMAN; PIGPC 1; PIGPC1; THW antibody TP53 apoptosis effector; Transmembrane protein THW.  
Specific References  (1)     |     bs-10783R has been referenced in 1 publications.
[IF=6.575] Qiyu Gan. et al. Prognostic Value and Immune Infiltration of HPV-Related Genes in the Immune Microenvironment of Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma. CANCERS. 2023 Jan;15(5):1419  IHC ;  Human.  
研究领域 细胞生物  信号转导  细胞凋亡  细胞骨架  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human,Mouse,Rat,Pig,Cow,Horse,Rabbit)
产品应用 WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, ICC=1:100-500, IF=1:100-500, ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 21kDa
细胞定位 细胞膜 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human p53 apoptosis effector related to PMP22: 101-193/193 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 PERP (PERP, TP53 Apoptosis Effector) is a Protein Coding gene. Diseases associated with PERP include Arrhythmogenic Right Ventricular Cardiomyopathy and Uveal Melanoma. Among its related pathways are Keratinization and p53 Pathway (RnD). An important paralog of this gene is TMEM47.

Function:
Component of intercellular desmosome junctions. Plays a role in stratified epithelial integrity and cell-cell adhesion by promoting desmosome assembly. Plays a role as an effector in the TP53-dependent apoptotic pathway.

Subcellular Location:
Cell junction, desmosome. Cell membrane; Multi-pass membrane protein. Note=Associated with desmosomes.

Tissue Specificity:
Expressed in skin, heart, placental, liver, pancreas, keratinocytes and dermal fibroblasts.

Similarity:
Belongs to the TMEM47 family.

SWISS:
Q96FX8

Gene ID:
64065

Database links:

Entrez Gene: 64065 Human

Entrez Gene: 64058 Mouse

Omim: 609301 Human

SwissProt: Q96FX8 Human

SwissProt: Q9JK95 Mouse

Unigene: 201446 Human

Unigene: 28209 Mouse



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