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Rabbit Anti-Norovirus Capsid protein VP1  antibody (bs-19320R)

~~~促销,代码KT240603~~~
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价
产品编号 bs-19320R
英文名称 Rabbit Anti-Norovirus Capsid protein VP1  antibody
中文名称 诺如病毒衣壳蛋白VP1抗体
别    名 Norovirus capsid protein; Norovirus Capsid protein VP1; CAPSD_NVN68; NVgp2; 58 kd capsid protein [Norwalk virus]; VP1; p59; Norwalk Viruses; Norwalk virus (strain GI/Human/United States/Norwalk/1968) (Hu/NV/NV/1968/US).  诺如病毒衣壳蛋白VP1; 诺瓦克病毒(Norwalk Viruses, NV);
研究领域 细菌及病毒  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Norovirus.)
产品应用 ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 58kDa
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from Norovirus Capsid protein VP1: 341-440/530 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 Norovirus is an RNA virus of the Caliciviridae taxonomic family, causes approximately 90% of epidemic non bacterial outbreaks of gastroenteritis around the world and is responsible for 50% of all foodborne outbreaks of gastroenteritis in the US. Norovirus affects people of all ages. The viruses are transmitted by faecally contaminated food or water and by person to person contact. Noroviruses can genetically be classified into 5 different genogroups (GI, GII, GIII, GIV, and GV) which can be further divided into different genetic clusters or genotypes. For example genogroup II, the most prevalent human genogroup, presently contains 19 genotypes. Genogroups I, II and IV infect humans, whereas genogroup III infects bovine species and genogroup V has recently been isolated in mice. Noroviruses contain a positive-sense RNA genome of approximately 7.5 kbp, encoding a major structural protein (VP1) of about 58~60 kDa and a minor capsid protein (VP2). The virus particles demonstrate an amorphous surface structure when visualized using electron microscopy and are between 27-38 nm in size.

Function:
Capsid protein self assembles to form an icosahedral capsid with a T=3 symmetry, about 38 nm in diameter, and consisting of 180 capsid proteins. A smaller form of capsid with a diameter of 23 nm might be capsid proteins assembled as icosahedron with T=1 symmetry. The capsid encapsulate the genomic RNA and VP2 proteins. Attaches virion to target cells by binding histo-blood group antigens present on gastroduodenal epithelial cells.

SWISS:
Q83884

Gene ID:
1491972

Database links:
Entrez Gene: 1491972 Norwalk virus

SwissProt: Q83884 Norwalk virus



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