| 产品编号 | bs-19403R |
| 英文名称 | PRPF38A Rabbit pAb |
| 中文名称 | mRNA前体剪接因子Prp38抗体 |
| 别 名 | 2410002M20Rik; FLJ14936; MGC3320; OTTMUSP00000008592; PR38A_HUMAN; Pre mRNA splicing factor 38A; Pre-mRNA-splicing factor 38A; Prp38; PRP38 pre mRNA processing factor 38(yeast) domain containing A; PRP38 pre mRNA processing factor 38 domain containing A; prpf38a; RGD1311129; RP23-406B13.4; RP5 965L7.1. |
| 研究领域 | 细胞生物 表观遗传学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | (predicted: Human,Mouse,Rat,Rabbit,Pig,Sheep,Cow,Zebrafish,Dog,Horse,Rhesus monkey,Gorilla, Orangutan,Xenopus tropicalis) |
| 产品应用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 37 kDa |
| 检测分子量 | |
| 细胞定位 | 细胞核 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human PRPF38A: 101-200/312 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
HPRP18 is a 342 amino acid protein that localizes to nuclear speckles and plays a role in the second step of pre-mRNA splicing. A member of the PRP18 family, PRPF18 contains seven WD repeats and exists as two alternatively spliced isoforms which are encoded by a gene located on human chromosome 10p13. Chromosome 10 contains over 800 genes and 135 million nucleotides. PTEN is an important tumor suppressor gene located on chromosome 10 and, when defective, causes a genetic predisposition to cancer development known as Cowden syndrome. Other chromosome 10 associated disorders include Cockayne syndrome, tetrahydrobiopterin deficiency and trisomy 10. Function: May be required for pre-mRNA splicing. Subcellular Location: Nucleus. Similarity: Belongs to the PRP38 family. SWISS: Q8NAV1 Gene ID: 84950 Database links: Entrez Gene: 456858 Chimpanzee Entrez Gene: 101137881 Gorilla Entrez Gene: 100050749 Horse Entrez Gene: 84950 Human Entrez Gene: 230596 Mouse Entrez Gene: 100171974 Orangutan Entrez Gene: 100356051 Rabbit Entrez Gene: 101115326 Sheep Entrez Gene: 432312 Xenopus laevis Entrez Gene: 549894 Xenopus tropicalis SwissProt: Q8NAV1 Human SwissProt: Q4FK66 Mouse SwissProt: Q5RDD2 Orangutan SwissProt: Q4FZQ6 Xenopus laevis SwissProt: Q28H87 Xenopus tropicalis Unigene: 5301 Human Unigene: 157534 Mouse Unigene: 413915 Mouse Unigene: 54468 Xenopus laevis |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
