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NUDT16 Rabbit pAb (bs-19512R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价
产品编号 bs-19512R
英文名称 NUDT16 Rabbit pAb
中文名称 NUDT16蛋白抗体
别    名 FLJ31265; FLJ34034; FLJ36248; Nucleoside diphosphate-linked moiety X motif 16; NUD16_HUMAN; Nudix(nucleoside diphosphate linked moiety X) type motif 16; Nudix motif 16; NUDT 16; NUDT16; U8 snoRNA-binding protein H29K; U8 snoRNA-decapping enzyme.  
研究领域 转录调节因子  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human,Rat)
产品应用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 22 kDa
检测分子量
细胞定位 细胞核 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human NUDT16: 51-150/195 
亚    型
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 NUDT16 (Nudix Hydrolase 16) is a Protein Coding gene. Among its related pathways are Metabolism and Purine metabolism (KEGG). GO annotations related to this gene include protein homodimerization activity and hydrolase activity. An important paralog of this gene is NUDT16L1.

Function:
RNA-decapping enzyme that binds specifically to U8 snoRNA. Part of the U8 snoRNP complex that is required for the accumulation of mature 5.8S and 28S rRNA. Has diphosphatase activity and removes m7G and m227G caps from U8 snoRNA. Has broad substrate specificity with manganese or cobalt as cofactor and can act on various RNA species (in vitro).

Subcellular Location:
Nucleus > nucleolus. Nucleus > nucleoplasm. Predominantly localized in nucleolus, and in a minor proportion in distinct foci in the nucleoplasm.

Similarity:
Belongs to the Nudix hydrolase family.
Contains 1 nudix hydrolase domain.

SWISS:
Q96DE0

Gene ID:
131870

Database links:

Entrez Gene: 131870 Human

Entrez Gene: 75686 Mouse

Entrez Gene: 363129 Rat

SwissProt: Q96DE0 Human

SwissProt: Q6P3D0 Mouse

SwissProt: B2RYV2 Rat

Unigene: 282050 Human

Unigene: 305810 Mouse



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