产品编号 | bs-20073R |
英文名称 | LY6G6F |
中文名称 | 淋巴细胞抗原6重复位点蛋白G6F抗体 |
别 名 | C6orf21; Chromosome 6 open reading frame 21; G6F; G6f protein [Precursor]; HCG43720, isoform CRA_c; LY66F_HUMAN; LY6G6D; Ly6g6f; Lymphocyte antigen 6 complex locus G6F; Lymphocyte antigen 6 complex locus protein G6f; Lymphocyte antigen 6 complex, locus G6D; NG32. |
Specific References (2) | bs-20073R has been referenced in 2 publications.
[IF=9.473] Li-Wei Liu. et al. Gut microbiota-derived nicotinamide mononucleotide alleviates acute pancreatitis by activating pancreatic SIRT3 signalling. BRIT J PHARMACOL. 2022 Nov;: IHC ; Rat, Mouse.
[IF=6.832] Zhang, Yaqi. et al. MicroRNA-146a-5p-modified human umbilical cord mesenchymal stem cells enhance protection against diabetic nephropathy in rats through facilitating M2 macrophage polarization. STEM CELL RES THER. 2022 Dec;13(1):1-16 IHC ; Rat.
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研究领域 | 细胞生物 信号转导 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | (predicted: Mouse,Rat) |
产品应用 | IHC-P=1:100-500, IHC-F=1:100-500, ICC=1:100-500, IF=1:100-500, ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理论分子量 | 32kDa |
细胞定位 | 细胞膜 |
性 状 | Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from rat LY6G6F: 101-200/293 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
缓 冲 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
产品介绍 |
lymphocyte antigen 6 complex locus protein G6f is a single-pass type I membrane protein belonging to the immunoglobulin (Ig) superfamily. Located in the class III region of the major histocompatibility complex (MHC), the G6f gene lies in a cluster of genes encoding cell-surface proteins that play a role in the immune system and cellular recognition. G6f functions as a downstream effector of GRB2 and GRB7, and, in humans, it interacts with GRB2 and GRB7 through the phosphorylation of a tyrosine residue (Tyr 281) in the intracellular tail of G6f. This interaction is also mediated by the SH2 domain of GRB2 and possibly that of GRB7. G6f is a 297 amino acid protein, and it forms a disulfide-linked homodimer. Function: May play a role in the downstream signal transduction pathways involving GRB2 and GRB7. Subcellular Location: Cell membrane. Post-translational modifications: modificationsN-glycosylated. Similarity: Contains 1 Ig-like V-type (immunoglobulin-like) domain. SWISS: Q6MG56 Gene ID: 309609 Database links: Entrez Gene: 259215 Human Entrez Gene: 433099 Mouse Omim: 611404 Human SwissProt: Q5SQ64 Human SwissProt: Q7Z5H2 Human Unigene: 591794 Human Unigene: 145028 Rat |
1、抗体溶解方法 | |
2、抗体修复方式 | |
3、常用试剂的配制 | |
4、免疫组化操作步骤 | |
5、免疫组化问题解答 | |
6、Western Blotting 操作步骤 | |
7、Western Blotting 问题解答 | |
8、关于肽链的设计 | |
9、多肽的溶解与保存 | |
10、酶标抗体效价测定程序 | |