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Rabbit Anti-SEC23IP  antibody (bs-19615R)
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价
产品编号 bs-19615R
英文名称 SEC23IP
中文名称 SEC23相互作用蛋白抗体
别    名 CDA II; CDAII; CDAN2; HEMPAS; Protein transport protein Sec23B; RP11-379J5.1; SC23B_HUMAN; Sec23 homolog B (S. cerevisiae); SEC23 related protein B; SEC23-like protein B; SEC23-related protein B; Sec23b; Transport protein SEC23B.  
研究领域 肿瘤  细胞生物  发育生物学  信号转导  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Rat,Rabbit,Sheep (predicted: Human,Mouse,Cow,Horse)
产品应用 IHC-P=1:100-500, IHC-F=1:100-500, ICC=1:100-500, IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 111kDa
细胞定位 细胞浆 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SEC23IP: 811-910/1000 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 This gene encodes a member of the phosphatidic acid preferring-phospholipase A1 family. The encoded protein is localized to endoplasmic reticulum exit sites and plays a critical role in ER-Golgi transport as part of the multimeric coat protein II complex. An orthologous gene in frogs is required for normal neural crest cell development, suggesting that this gene may play a role in Waardenburg syndrome neural crest defects. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Feb 2011]

Function:
Plays a role in the organization of endoplasmic reticulum exit sites.

Subcellular Location:
Cytoplasmic vesicle > COPII-coated vesicle membrane. Endoplasmic reticulum.

Tissue Specificity:
Ubiquitously expressed with stronger levels detected in heart, liver and skeletal muscle.

Similarity:
Belongs to the PA-PLA1 family.
Contains 1 DDHD domain.
Contains 1 SAM (sterile alpha motif) domain.

SWISS:
Q9Y6Y8

Gene ID:
11196

Database links:

Entrez Gene: 11196 Human

Entrez Gene: 207352 Mouse

Entrez Gene: 309010 Rat

SwissProt: Q9Y6Y8 Human

SwissProt: Q6NZC7 Mouse

Unigene: 435004 Human

Unigene: 667094 Human

Unigene: 297105 Mouse



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