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Rabbit Anti-SFMBT1  antibody (bs-19682R)
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价
产品编号 bs-19682R
英文名称 SFMBT1
中文名称 SFMBT1蛋白抗体
别    名 DKFZp434L243; MGC93349; OTTMUSP00000030378; OTTMUSP00000030379; OTTMUSP00000030381; Renal ubiquitous protein 1; RU1; Scm like with four mbt domains 1; Scm like with four MBT domains protein 1; Scm related gene containing four mbt domains; Scm related gene product containing four mbt domains; Scm-like with four MBT domains protein 1; SFMBT; SFMBT 1; Sfmbt1; SMBT1_HUMAN; Smr.  
研究领域 细胞生物  信号转导  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human,Mouse,Rat)
产品应用 IHC-P=1:100-500, IHC-F=1:100-500, ICC=1:100-500, IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 98kDa
细胞定位 细胞核 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SFMBT1: 131-230/866 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 This gene shares high similarity with the Drosophila Scm (sex comb on midleg) gene. It encodes a protein which contains four malignant brain tumor repeat (mbt) domains and may be involved in antigen recognition. [provided by RefSeq, Jun 2012]

Function:
Histone-binding protein, which is part of various corepressor complexes. Mediates the recruitment of corepressor complexes to target genes, followed by chromatin compaction and repression of transcription. Plays a role during myogenesis: required for the maintenance of undifferentiated states of myogenic progenitor cells via interaction with MYOD1. Interaction with MYOD1 leads to the recruitment of associated corepressors and silencing of MYOD1 target genes. Part of the SLC complex in germ cells, where it may play a role during spermatogenesis.

Tissue Specificity:
Expressed in all cell lines and normal tissues tested, including the thymus.

Similarity:
Contains 4 MBT repeats.
Contains 1 SAM (sterile alpha motif) domain.

SWISS:
Q9UHJ3

Gene ID:
51460

Database links:

Entrez Gene: 51460 Human

Entrez Gene: 54650 Mouse

Entrez Gene: 58967 Rat

Omim: 607319 Human

SwissProt: Q9UHJ3 Human

SwissProt: Q9JMD1 Mouse

SwissProt: Q9JMD2 Rat

Unigene: 343679 Human

Unigene: 294662 Mouse

Unigene: 14839 Rat



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