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Rabbit Anti-RASEF  antibody (bs-19733R)
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价
产品编号 bs-19733R
英文名称 RASEF
中文名称 ras基因相关蛋白Rab45抗体
别    名 FLJ31614; RAB45; RAB45 member RAS oncogene family; RASEF_HUMAN; RAS and EF hand domain containing; RAS and EF hand domain containing protein; Ras related protein Rab 45.  
研究领域 肿瘤  细胞生物  信号转导  G蛋白偶联受体  G蛋白信号  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human,Mouse)
产品应用 ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 83kDa
细胞定位 细胞浆 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human RASEF: 551-650/740 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 This gene is a member of the Rab family of GTPases that are involved in regulation of membrane traffic. The encoded protein contains an N-terminal EF-hand domain, a coiled-coil motif and a C-terminal Rab domain. A potential role as tumor suppressor has been indicated for this gene. [provided by RefSeq, Nov 2012]

Function:
Binds predominantly GDP, and also GTP.

Subcellular Location:
Cytoplasm, perinuclear region.

Tissue Specificity:
Down-regulated in cutaneous melanoma cells but not in breast cancer cells.

Similarity:
Belongs to the small GTPase superfamily. Rab family.

SWISS:
Q8IZ41

Gene ID:
158158

Database links:

Entrez Gene: 158158 Human

Entrez Gene: 242505 Mouse

Omim: 611344 Human

SwissProt: Q8IZ41 Human

SwissProt: Q5RI75 Mouse

Unigene: 657750 Human

Unigene: 487185 Mouse



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