产品编号 | bs-19911R |
英文名称 | PCDH19 Rabbit pAb |
中文名称 | 原钙粘附蛋白19抗体 |
别 名 | KIAA1313; PCD19_HUMAN; PCDH19; Protocadherin 19; Protocadherin-19. |
研究领域 | 细胞生物 细胞粘附分子 细胞膜蛋白 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
克 隆 号 | |
交叉反应 | Human (predicted: Mouse,Rat,Rabbit,Sheep,Cow,Dog,Horse) |
产品应用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理论分子量 | 124 kDa |
检测分子量 | |
细胞定位 | 细胞膜 |
性 状 | Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human PCDH19: 151-250/1148 <Extracellular> |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
缓 冲 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
产品介绍 |
The protein encoded by this gene is a member of the delta-2 protocadherin subclass of the cadherin superfamily. The encoded protein is thought to be a calcium-dependent cell-adhesion protein that is primarily expressed in the brain. Defects in this gene are a cause of epilepsy female-restricted with mental retardation (EFMR). Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, May 2010] Function: Potential calcium-dependent cell-adhesion protein. Subcellular Location: Cell membrane. Tissue Specificity: Moderately expressed in all regions of the brain examined, with lowest levels found in the cerebellum. Moderate expression is also found in ovary, and low expression in all other tissues tested. Also detected in primary skin fibroblast. DISEASE: Epileptic encephalopathy, early infantile, 9 Similarity: Contains 6 cadherin domains. SWISS: Q8TAB3 Gene ID: 57526 Database links: Entrez Gene: 57526 Human Entrez Gene: 101125719 Gorilla Entrez Gene: 100059478 Horse Entrez Gene: 279653 Mouse Omim: 300460 Human SwissProt: Q8TAB3 Human SwissProt: Q80TF3 Mouse Unigene: 4993 Human Unigene: 39738 Mouse |
产品图片 | |
1、抗体溶解方法 | |
2、抗体修复方式 | |
3、常用试剂的配制 | |
4、免疫组化操作步骤 | |
5、免疫组化问题解答 | |
6、Western Blotting 操作步骤 | |
7、Western Blotting 问题解答 | |
8、关于肽链的设计 | |
9、多肽的溶解与保存 | |
10、酶标抗体效价测定程序 | |