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Rabbit Anti-PP11  antibody (bs-21050R)
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价
产品编号 bs-21050R
英文名称 PP11
中文名称 胎盘蛋白11抗体
别    名 22 serine protease; 26 serine protease; Endonuclease, polyU-specific; endou; ENDOU_HUMAN; P11; Placental protein 11; Poly(U)-specific endoribonuclease; PP11; Pp11r; Protein endoU; PRSS26; Uridylate-specific endoribonuclease.  
研究领域 细胞生物  发育生物学  信号转导  表观遗传学  泛素  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human,Mouse,Rat)
产品应用 IHC-P=1:100-500, IHC-F=1:100-500, ICC=1:100-500, IF=1:100-500, ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 47kDa
细胞定位 分泌型蛋白 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PP11: 161-260/410 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 This gene encodes a protein with protease activity and is expressed in the placenta. The protein may be useful as a tumor marker. Multiple alternatively spliced transcript variants have been found for this protein. [provided by RefSeq, Feb 2010]

Function:
Endoribonuclease that cleaves single-stranded RNAs at uridylates and releases products that have 2'-3'-cyclic phosphate termini.

Subcellular Location:
Secreted.

Tissue Specificity:
Placental-specific, but also associated with various malignant neoplasms.

Post-translational modifications:
It has been suggested that the active SMB domain may be permitted considerable disulfide bond heterogeneity or variability, thus two alternate disulfide patterns based on 3D structures are described with 1 disulfide bond conserved in both.

Similarity:
Belongs to the ENDOU family.
Contains 2 SMB (somatomedin-B) domains.

SWISS:
P21128

Gene ID:
8909

Database links:

Entrez Gene: 525399 Cow

Entrez Gene: 8909 Human

Entrez Gene: 19011 Mouse

Entrez Gene: 680317 Rat

Omim: 606720 Human

SwissProt: A6QLQ8 Cow

SwissProt: P21128 Human

SwissProt: Q3V188 Mouse

Unigene: 997 Human

Unigene: 1001 Mouse



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