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Rabbit Anti-p39/CDK5R2  antibody (bs-21065R)
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价
产品编号 bs-21065R
英文名称 p39/CDK5R2
中文名称 细胞周期蛋白依赖性激酶5调节亚基2抗体
别    名 CD5R2_HUMAN; CDK5 activator 2; Cdk5r2; Cyclin dependent kinase 5 activator 2; Cyclin dependent kinase 5 regulatory subunit 2; Cyclin-dependent kinase 5 activator 2; Cyclin-dependent kinase 5 regulatory subunit 2; NCK5AI; p39; P39I; p39nck5ai.  
研究领域 细胞生物  神经生物学  信号转导  细胞周期蛋白  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human,Mouse,Rat,Pig,Cow,Horse,Sheep)
产品应用 IHC-P=1:100-500, IHC-F=1:100-500, ICC=1:100-500, IF=1:100-500, ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 38kDa
细胞定位 细胞膜 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human p39/CDK5R2: 251-350/367 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 The protein encoded by this gene is a neuron-specific activator of CDK5 kinase. It associates with CDK5 to form an active kinase. This protein and neuron-specific CDK5 activator CDK5R1/p39NCK5A both share limited similarity to cyclins, and thus may define a distinct family of cyclin-dependent kinase activating proteins. [provided by RefSeq, Jul 2008]

Function:
Activator of CDK5/TPKII.

Subunit:
Heterodimer of a catalytic subunit and a regulatory subunit.

Tissue Specificity:
Brain and neuron specific.

Post-translational modifications:
Myristoylated. The Gly-2-Ala mutant is absent of the cell periphery, suggesting that a proper myristoylation signal is essential for the proper distribution of CDK5R2 (p39).

Similarity:
Belongs to the cyclin-dependent kinase 5 activator family.

SWISS:
Q13319

Gene ID:
21065

Database links:

Entrez Gene: 8941 Human

Entrez Gene: 12570 Mouse

Omim: 603764 Human

SwissProt: Q13319 Human

SwissProt: O35926 Mouse

Unigene: 158460 Human

Unigene: 153833 Mouse



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