| 产品编号 | bs-9969R |
| 英文名称 | PDE1C |
| 中文名称 | 磷酸二酯酶1C抗体 |
| 别 名 | 5''-cyclic nucleotide phosphodiesterase 1C; Calcium/calmodulin dependent 3'5' cyclic nucleotide phosphodiesterase 1C; Calcium/calmodulin-dependent 3''; Cam PDE 1C; Cam-PDE 1C; hCam 3; hCam-3; HCAM3; HSPDE1C1A; Human 3'5' cyclic nucleotide Phosphodiesterase; PDE 1C; Pde1c; PDE1C_HUMAN; Phosphodiesterase 1C; Phosphodiesterase 1C calmodulin dependent; Phosphodiesterase 1C calmodulin dependent 70kDa. |
| 研究领域 | 细胞生物 染色质和核信号 信号转导 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | (predicted: Human,Mouse,Rat) |
| 产品应用 | IHC-P=1:100-500, IHC-F=1:100-500, ICC=1:100-500, IF=1:100-500, ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 81kDa |
| 细胞定位 | 细胞浆 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human PDE1C: 71-170/709 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
Cyclic nucleotide phosphodiesterases (PDEs) catalyze hydrolysis of the cyclic nucleotides cAMP and cGMP to the corresponding nucleoside 5-prime-monophosphates. Mammalian PDEs have been classified into several families based on their biochemical properties. Members of the PDE1 family, such as PDE1C, are calmodulin (see MIM 114180)-dependent PDEs (CaM-PDEs) that are stimulated by a calcium-calmodulin complex (Repaske et al., 1992 [PubMed 1326532]).[supplied by OMIM, Oct 2009] Function: Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Has a high affinity for both cAMP and cGMP. Subcellular Location: Cytoplasm. Tissue Specificity: Expressed in several tissues, including brain and heart. Similarity: Belongs to the cyclic nucleotide phosphodiesterase family. PDE1 subfamily. SWISS: Q14123 Gene ID: 5137 Database links: Entrez Gene: 5137 Human Entrez Gene: 18575 Mouse Omim: 602987 Human SwissProt: Q14123 Human SwissProt: Q64338 Mouse Unigene: 728862 Human Unigene: 5145 Mouse Unigene: 10289 Rat |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
