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Rabbit Anti-SLC16A12  antibody (bs-21198R)
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价
产品编号 bs-21198R
英文名称 SLC16A12
中文名称 溶质载体家族16成员12抗体
别    名 CJMG; DKFZp686E188; MCT 12; MCT12; Monocarboxylate transporter 12; MOT12_HUMAN; OTTHUMP00000020064; Slc16a12; Solute carrier family 16 member 12; Solute carrier family 16, member 12 (monocarboxylic acid transporter 12).  
研究领域 肿瘤  细胞生物  神经生物学  信号转导  细胞膜蛋白  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human,Mouse,Dog,Pig,Cow,Horse)
产品应用 IHC-P=1:100-500, IHC-F=1:100-500, ICC=1:100-500, IF=1:100-500, ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 53kDa
细胞定位 细胞膜 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SLC16A12: 401-486/486 <Cytoplasmic>
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 This gene encodes a transmembrane transporter that likely plays a role in monocarboxylic acid transport. A mutation in this gene has been associated with juvenile cataracts with microcornea and renal glucosuria. [provided by RefSeq, Mar 2010]

Function:
Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates.

Subcellular Location:
Cell membrane.

Tissue Specificity:
Most highly expressed in kidney, followed by retina, lung, and testis. Very weakly expressed in brain and liver. Also detected in lens.

DISEASE:
Defects in SLC16A12 are a cause of cataract juvenile with microcornea and glucosuria (CJMG) [MIM:612018]. Renal glucosuria is defined by elevated glucose level in the urine without hyperglycemia and without evidence of morphological renal anomalies.

Similarity:
Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.

SWISS:
Q6ZSM3

Gene ID:
387700

Database links:

Entrez Gene: 387700 Human

Entrez Gene: 240638 Mouse

Entrez Gene: 309525 Rat

Omim: 611910 Human

SwissProt: Q6ZSM3 Human

SwissProt: Q8BGC3 Mouse

Unigene: 530338 Human

Unigene: 74636 Mouse



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