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SLC30A2 Rabbit pAb (bs-21252R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价

产品编号 bs-21252R
英文名称 SLC30A2 Rabbit pAb
中文名称 溶质载体转运蛋白家族30成员2抗体
别    名 SLC30A2; Solute carrier family 30(Zinc Transporter) member 2; Solute carrier family 30 member 2; Zinc transporter 2; ZnT-2; ZNT2_HUMAN.  
研究领域 肿瘤  细胞生物  信号转导  转运蛋白  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human
产品应用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 35 kDa
检测分子量
细胞定位 细胞膜 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SLC30A2: 21-120/323 <Cytoplasmic>
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 The protein encoded by this gene is a zinc transporter that acts as a homodimer. The encoded protein plays a role in secreting zinc into breast milk. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2015]

Subcellular Location:
Lysosome membrane and Vacuole membrane.

DISEASE:
The disease is caused by mutations affecting the gene represented in this entry.
Disease description:A disorder occurring in breast-fed infants as a consequence of low milk zinc concentration in their nursing mothers, which cannot be corrected by maternal zinc supplementation. A large amount of zinc, an essential trace mineral, is required for normal growth particularly in infants, and breast milk normally contains adequate zinc to meet the requirement for infants up to 4 to 6 months of age. Zinc deficiency can lead to dermatitis, alopecia, decreased growth, and impaired immune function. The disorder shows autosomal dominant inheritance with incomplete penetrance.

Similarity:
Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
SLC30A subfamily.

SWISS:
Q9BRI3

Gene ID:
7780

Database links:

Entrez Gene: 7780 Human

Omim: 609617 Human

SwissProt: Q9BRI3 Human

Unigene: 143545 Human



产品图片
Paraformaldehyde-fixed, paraffin embedded (Human ovarian); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (SLC30A2) Polyclonal Antibody, Unconjugated (bs-21252R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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