| 产品编号 | bs-20614R |
| 英文名称 | NRXN3 Rabbit pAb |
| 中文名称 | 轴突蛋白3抗体 |
| 别 名 | Neurexin III-alpha; NRXN3; NRXN 3; NRXN-3; C14orf60; Neurexin 3; Neurexin3; Neurexin-3; Neurexin III; Neurexin III-alpha; Neurexin-3-alpha [Precursor]; NRX3A_HUMAN. |
| 研究领域 | 神经生物学 细胞粘附分子 细胞膜蛋白 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 克 隆 号 | |
| 交叉反应 | Human (predicted: Mouse,Rat,Rabbit,Pig,Sheep,Cow,Dog,Horse) |
| 产品应用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 178 kDa |
| 检测分子量 | |
| 细胞定位 | 细胞膜 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human NRXN3: 28-120/1643 <Extracellular> |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
This gene encodes a member of a family of proteins that function in the nervous system as receptors and cell adhesion molecules. Extensive alternative splicing and the use of alternative promoters results in multiple transcript variants and protein isoforms for this gene, but the full-length nature of many of these variants has not been determined. Transcripts that initiate from an upstream promoter encode alpha isoforms, which contain epidermal growth factor-like (EGF-like) sequences and laminin G domains. Transcripts initiating from the downstream promoter encode beta isoforms, which lack EGF-like sequences. Genetic variation at this locus has been associated with a range of behavioral phenotypes, including alcohol dependence and autism spectrum disorder. [provided by RefSeq, Dec 2012] Function: Neuronal cell surface protein that may be involved in cell recognition and cell adhesion. May play a role in angiogenesis. Subunit: The cytoplasmic C-terminal region binds to CASK. Binds to neuroligins NLGN1, NLGN2 and NLGN3. Subcellular Location: Membrane; Single-pass type I membrane protein (Potential). Tissue Specificity: Expressed in the blood vessel walls (at protein level). Post-translational modifications: Proccessed by alpha-secretase leading to the formation of an extracellular soluble protein as well as a C-terminal membrane-embedded fragment (CTF). Proteolysis of these CTFs by gamma-secretase releases intracellular domains (ICDs) and extracellular peptides. Similarity: Belongs to the neurexin family. Contains 1 laminin G-like domain. SWISS: Q9Y4C0 Gene ID: 9369 Database links: Entrez Gene: 9369 Human Entrez Gene: 18191 Mouse Omim: 600567 Human SwissProt: Q9HDB5 Human SwissProt: Q9Y4C0 Human SwissProt: Q6P9K9 Mouse SwissProt: Q8C985 Mouse SwissProt: Q8CCT8 Mouse |
| 产品图片 |
Sample:
Hela(Human) Cell Lysate at 40 ug
Primary: Anti-alpha smooth muscle Actin (bs-10196R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 178 kD
Observed band size: 117 kD
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| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
