| 产品编号 | bs-8741R |
| 英文名称 | SNRPN |
| 中文名称 | 小核糖核蛋白N抗体 |
| 别 名 | HCERN3; PWCR; RSMN_HUMAN; RT LI; RTLI; SM D; Sm N; Sm protein D; Sm protein N; Sm-D; Sm-N; Small nuclear ribonucleoprotein associated protein N; Small nuclear ribonucleoprotein polypeptide N; Small nuclear ribonucleoprotein-associated protein N; SMD; SmN; SNRNP N; snRNP-N; SNRNPN; SNRPN; SNURF SNRPN; Tissue specific splicing protein; Tissue-specific-splicing protein. |
| 研究领域 | 细胞生物 转录调节因子 表观遗传学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | (predicted: Human,Mouse,Rat,Pig,Cow,Horse,Rabbit,Sheep) |
| 产品应用 | ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 25kDa |
| 细胞定位 | 细胞核 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human SNRPN: 1-100/240 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 |
| 保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
This gene is located within the Prader-Willi Syndrome critical region on chromosome 15 and is imprinted and expressed from the paternal allele. It encodes a component of the small nuclear ribonucleoprotein complex, which functions in pre-mRNA processing and may contribute to tissue-specific alternative splicing. Alternative promoter use and alternative splicing result in a multitude of transcript variants encoding the same protein. Transcript variants that initiate at the CpG island-associated imprinting center may be bicistronic and also encode the SNRPN upstream reading frame protein (SNURF) from an upstream open reading frame. In addition, long spliced transcripts for small nucleolar RNA host gene 14 (SNHG14) may originate from the promoters at this locus and share exons with this gene. Alterations in this region are associated with parental imprint switch failure, which may cause Angelman syndrome or Prader-Willi syndrome. [provided by RefSeq, Mar 2017] Function: May be involved in tissue-specific alternative RNA processing events. Subcellular Location: Nucleus. Tissue Specificity: Expressed in brain and lymphoblasts. Similarity: Belongs to the snRNP SmB/SmN family. SWISS: P63162 Gene ID: 6638 Database links: Entrez Gene: 6638 Human Entrez Gene: 20646 Mouse Entrez Gene: 84704 Mouse Omim: 182279 Human SwissProt: Q60HD3 Cynomolgus Monkey SwissProt: P63162 Human SwissProt: P63163 Mouse SwissProt: Q5R6I0 Orangutan Unigene: 555970 Human Unigene: 564847 Human Unigene: 578619 Human Unigene: 585703 Human Unigene: 592473 Human Unigene: 621316 Human Unigene: 632166 Human Unigene: 728856 Human Unigene: 274995 Mouse Unigene: 11169 Rat |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
