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Rabbit Anti-ELP3  antibody (bs-20539R)
~~~促销,代码KX240301~~~
~~~促销,代码KX240302~~~
订购热线:400-901-9800
订购邮箱:sales@bioss.com.cn
订购QQ:  400-901-9800
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价
产品编号 bs-20539R
英文名称 ELP3
中文名称 组蛋白乙酰转移酶KAT9抗体
别    名 ELP3_HUMAN; Elongator complex protein 3; EC:2.3.1.-; hELP3; tRNA uridine(34) acetyltransferase; elongator acetyltransferase complex subunit 3; KAT9;   
Specific References  (1)     |     bs-20539R has been referenced in 1 publications.
[IF=5.753] Xiaojun Zhang. et al. TSP50 promotes hepatocyte proliferation and tumour formation by activating glucose‐6‐phosphate dehydrogenase (G6PD). 2021 Feb 25  IP ;  Human.  
研究领域 细胞生物  转录调节因子  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human,Mouse,Dog,Pig,Cow,Sheep)
产品应用 WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, ICC=1:100-500, IF=1:100-500, ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 62kDa
细胞定位 细胞核 细胞浆 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ELP3: 1-100/547 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 ELP3 is the catalytic subunit of the histone acetyltransferase elongator complex, which contributes to transcript elongation and also regulates the maturation of projection neurons (Creppe et al., 2009 [PubMed 19185337]).[supplied by OMIM, Apr 2009]

Function:
Catalytic histone acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4. May also have a methyltransferase activity.

Subcellular Location:
Cytoplasm. Nucleus.

Similarity:
Belongs to the ELP3 family.
Contains 1 N-acetyltransferase domain.

SWISS:
Q9H9T3

Gene ID:
55140

Database links:

Entrez Gene: 55140 Human

Entrez Gene: 74195 Mouse

SwissProt: Q9H9T3 Human

SwissProt: Q9CZX0 Mouse



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