产品编号 |
bs-10889P |
英文名称 |
Recombinant human PCNA protein, C-His
|
中文名称 |
重组人增殖细胞核抗原蛋白 |
别 名 |
Proliferation Marker; Cyclin; DNA polymerase delta auxiliary protein; HGCN8729; MGC8367; Mutagen-sensitive 209 protein; Pcna/cyclin; PCNAR; Polymerase delta accessory protein; Proliferating Cell Nuclear Antigen; PCNA_HUMAN; Recombinant human PCNA protein, C-His |
理论分子量 |
30 kDa |
检测分子量 |
35 |
性 状 |
Lyophilized or Liquid |
浓 度 |
>0.5 mg/ml |
物 种 |
Human |
序 列 |
1-261/261 |
纯 度 |
>95% as determined by SDS-PAGE |
纯化方法 |
AC |
内毒素 |
Not analyzed |
表达系统 |
E.coli |
活性 |
Not tested |
标签 |
C-His |
缓 冲 液 |
20mM Tris-HCl (pH8.0). |
保存条件 |
Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
注意事项 |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
产品介绍 |
The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. [provided by RefSeq, Jul 2008].
|
产品图片 |
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.
|
|
|