产品编号 |
bs-20439P |
英文名称 |
Recombinant Insulin Detemir protein (HEK293)
|
中文名称 |
重组地特胰岛素 |
别 名 |
D04539; Insulin detemir (genetical recombination); Insulin detemir (usan/inn); Levemir; Levemir (tn); Levemir (tn) USP/EP/BP; Recombinant Insulin Detemir protein (HEK293); CAS: 169148-63-4; 可溶性的长效人胰岛素类似物; |
克 隆 号 |
|
理论分子量 |
5.917 kDa |
检测分子量 |
5.9 |
性 状 |
Lyophilized or Liquid |
浓 度 |
>0.5 mg/ml |
物 种 |
Unknown |
序 列 |
Unknown |
纯 度 |
>95% as determined by SDS-PAGE |
纯化方法 |
AC |
内毒素 |
Not analyzed |
表达系统 |
HEK293 cell |
活性 |
Yes |
标签 |
Tag free |
缓 冲 液 |
Lyophilized powder. |
保存条件 |
Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
注意事项 |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
产品介绍 |
This gene encodes insulin, a peptide hormone that plays a vital role in the regulation of carbohydrate and lipid metabolism. After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified, including insulin-dependent diabetes mellitus, permanent neonatal diabetes diabetes mellitus, maturity-onset diabetes of the young type 10 and hyperproinsulinemia. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. [provided by RefSeq, May 2020]
|
|
|