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Rabbit Anti-GST1  antibody (bs-24109R)
~~~促销,代码KX240301~~~
~~~促销,代码KX240302~~~
订购热线:400-901-9800
订购邮箱:sales@bioss.com.cn
订购QQ:  400-901-9800
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价
产品编号 bs-24109R
英文名称 GST1
中文名称 谷胱甘肽转移酶抗体
别    名 Glutathione S-Transferase Mu 1; Glutathione S-Transferase M1; GST HB Subunit 4; GST Class-Mu 1; EC 2.5.1.18; GSTM1a-1a; GSTM1b-1b; GSTM1-1; GST1; GTH4; S-(Hydroxyalkyl)Glutathione Lyase; Glutathione S-Aralkyltransferase; Glutathione S-Alkyltransferase; Glutathione S-Aryltransferase; HB Subunit 4; GTM1; MU-1; H-B; MU; GSTM1_MOUSE;   
研究领域 肿瘤  细胞生物  免疫学  信号转导  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Mouse,Rat)
产品应用 WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, ICC=1:100-500, IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 26kDa
细胞定位 细胞浆 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from mouse GST1: 51-150/218 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Null mutations of this class mu gene have been linked with an increase in a number of cancers, likely due to an increased susceptibility to environmental toxins and carcinogens. Multiple protein isoforms are encoded by transcript variants of this gene. [provided by RefSeq, Jul 2008]

Function:
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.

Subunit:
Homodimer.

Subcellular Location:
Cytoplasm

Tissue Specificity:
Liver (at protein level).

Similarity:
Belongs to the GST superfamily. Mu family.

SWISS:
P10649

Gene ID:
14862

Database links:

HGNC: 4632 Human

Entrez Gene: 2944 Human

Entrez Gene: 14862 Mouse

UniProtKB: P09488 Human

UniProtKB: P10649 Mouse

OMIM: 138350 Human



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