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MouseAnti-human CD3 antibody (bsm-30092M)
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说明书: 100ug  
100ug/1880.00元
大包装/询价
产品编号 bsm-30092M
英文名称 human CD3
中文名称 小鼠抗人CD3单克隆抗体
别    名 CD3 epsilon; CD3e; CD3e antigen epsilon polypeptide (TiT3 complex); CD3E antigen epsilon polypeptide; CD3E antigen, epsilon subunit; CD3e molecule epsilon; CD3e molecule, epsilon (CD3 TCR complex); CD3e molecule, epsilon (CD3-TCR complex); CD3E_HUMAN; IMD18; T cell antigen receptor complex epsilon subunit of T3; T cell surface antigen T3/Leu 4 epsilon chain; T cell surface glycoprotein CD3 epsilon chain; T-cell surface antigen T3/Leu-4 epsilon chain; T-cell surface glycoprotein CD3 epsilon chain; T3E; TCRE.  
Specific References  (1)     |     bsm-30092M has been referenced in 1 publications.
[IF=9.918] 222Daijun Zhou. et al. An injectable miR181a-IFI6 nanoparticles promote high-quality healing of radiation-induced skin injury. MATER TODAY ADV. 2022 Aug;15:100267  FC ;  Human.  
研究领域 肿瘤  细胞生物  免疫学  细胞表面分子  t-淋巴细胞  
抗体来源 Mouse
克隆类型 Monoclonal
克 隆 号 HIT3b
交叉反应 (predicted: Human, )
产品应用 Flow-Cyt=5ul/Test 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 20kDa
检测分子量 20
细胞定位 细胞膜 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CD3 
亚    型 Mouse IgG2a, k
纯化方法 Affinity purified by Protein G
缓 冲 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008].

Function:
The CD3 complex mediates signal transduction.

Subunit:
The TCR/CD3 complex of T-lymphocytes consists of either a TCR alpha/beta or TCR gamma/delta heterodimer coexpressed at the cell surface with the invariant subunits of CD3 labeled gamma, delta, epsilon, zeta, and eta.

Subcellular Location:
Membrane; Single-pass type I membrane protein.

Similarity:
Contains 1 Ig-like (immunoglobulin-like) domain.
Contains 1 ITAM domain.

SWISS:
P07766

Gene ID:
916

Database links:

Entrez Gene: 916 Human

Entrez Gene: 12501 Mouse

Omim: 186830 Human

SwissProt: P07766 Human

SwissProt: P22646 Mouse

Unigene: 3003 Human

Unigene: 210361 Mouse



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