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Mouse Anti-human CD45/FITC antibody (BF00401)
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说明书: 下载
25T/480.00元
50T/880.00元
100T/1480.00元
大包装/询价
产品编号 BF00401
英文名称 Mouse Anti-human CD45/FITC antibody
中文名称 FITC标记小鼠抗人CD45单克隆抗体
别    名 B220; CD 45; CD-45; cd45 antigen; ec3.1.3.48; CD45R; GP180; GP180; GP 180; L CA; LCA; L-CA; Leukocyte common antigen; LY5; Ly-5 glycoprotein; Protein tyrosine phosphatase receptor type C; Protein tyrosine phosphatase receptor type c polypeptide; protein tyrosine phosphatase, receptor type, C; Receptor-type tyrosine-protein phosphatase C; PTPRC; PTPRC_HUMAN; SCID due to PTPRC deficiency; T200; T200 glycoprotein; T200 leukocyte common antigen; Human homolog of severe combined immunodeficiency due to PTPRC deficiency.  
抗体来源 Mouse
克隆类型 Monoclonal
克 隆 号 HI30
交叉反应
产品应用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 143kDa
检测分子量 180-220
性    状 Liquid
免 疫 原 Recombinant human CD45 
亚    型 Mouse IgG2a, k
纯化方法 Affinity purified by Protein G
缓 冲 液 0.01M PBS, 0.5%BSA, 0.03% Proclin300
保存条件 Store at 2-8℃. Protect from light. Avoid freezing.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jun 2012

SWISS:
P08575

Gene ID:
5788

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