| 产品编号 | bsk11010 |
| 英文名称 | Human IL-10 ELISA Kit |
| 中文名称 | 白细胞介素10酶联免疫试剂盒 |
| 别 名 | Interleukin-10 precursor; Cytokine synthesis inhibitory factor; CSIF; Cytokine Synthesis Inhibitory Factor; IL 10; IL10A; Interleukin 10; Interleukin10; MGC126450; MGC126451; TGIF; IL10_HUMAN. |
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Specific References (6) | bsk11010 has been referenced in 6 publications.
[IF=17.521] Lizhen He. et al. Metabolic Reprogramming of NK Cells by Black Phosphorus Quantum Dots Potentiates Cancer Immunotherapy. Advanced Science. 2023 Jan;:2202519 ELISA ; Human.
[IF=12.479] Qi Chen. et al. Ruthenium complexes boost NK cell immunotherapy via sensitizing triple-negative breast cancer and shaping immuno-microenvironment. Biomaterials. 2022 Jan;:121371 ELISA ; Human.
[IF=10.273] Lai H et al. Selenium-containing ruthenium complex synergizes with natural killer cells to enhance immunotherapy against prostate cancer via activating TRAIL/FasL signaling. Biomaterials. 2019 Jul 24;219:119377. ELISA ; Human.
[IF=8.702] Zhang Mengqi. et al. Exosomal Mir-3613-3p derived from oxygen–glucose deprivation-treated brain microvascular endothelial cell promotes microglial M1 polarization. CELL MOL BIOL LETT. 2023 Dec;28(1):1-14 ELISA ; Human.
[IF=8.079] Qiu, Zhenhua. et al. Human umbilical cord mesenchymal stem cell-derived exosomal miR-335-5p attenuates the inflammation and tubular epithelial–myofibroblast transdifferentiation of renal tubular epithelial cells by reducing ADAM19 protein levels. STEM CELL RES THER. 2022 Dec;13(1):1-15 WB ; Human.
[IF=5.999] Cheng Chen. et al. Effects of substrate topography on the regulation of human fibroblasts and capsule formation via modulating macrophage polarization. COLLOID SURFACE B. 2023 Feb;222:113086 ELISA ; Human.
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| 种 属 | Human |
| 线性范围 | 7.8 - 500 pg/mL |
| 应用范围 | S/P/CC |
| 检测限 | 4 pg/mL |
| 适用样品基质 | cell culture supernates, serum, and plasma. |
| 保存条件 | Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Shipped with wet ice.) |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 |
IL-10 protein is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. 白细胞介素-10(IL-10)是主要由Th2细胞所产生的一种细胞因子，活化的B细胞、单核巨噬细胞和枯否氏细胞（Kupffer's cell）等也可产生IL-10。它是以抑制Th细胞克隆细胞因子合成为特点的多效免疫调节因子。 白介素-10是维护细胞因子网络平衡的重要负调节因子。其作用机制可能是降低抗原递呈细胞MHCⅡ类抗原表达，或诱导抗原递呈细胞产生另一种细胞因子，改变细胞内信号传递途径，从而选择性抑制某些细胞因子mRNA转录，并与Th2细胞产生的IL-4、IL-5有协同作用。 |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
