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Rabbit Anti-TNMD antibody (bs-41215R)
~~~促销,代码SQ220725~~~
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说明书: 50ul  100ul  200ul
50ul/1098.00元
100ul/1880.00元
200ul/2900.00元
大包装/询价

产品编号 bs-41215R
英文名称 TNMD
中文名称 腱调蛋白/软骨调节素样1蛋白抗体
别    名 BRICD4; BRICHOS domain containing 4; CHM1 LIKE; CHM1L; Chondromodulin I like; Chondromodulin I like protein; Chondromodulin-1-like protein; Chondromodulin-I-like protein; hChM1L; hTeM; Myodulin; TEM; Tendin; Tenomodulin; Tenomodulin protein; TNMD; TNMD_HUMAN; UNQ771/PRO1565.  
研究领域 心血管  血管内皮细胞  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, 
产品应用 WB=1:500-2000 IHC-P=1:400-800 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 37kDa
细胞定位 细胞核 细胞浆 细胞膜 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 Recombinant human TNMD protein 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 This gene encodes a protein that is related to chondromodulin-I, which is a cartilage-specific glycoprotein that functions to stimulate chondrocyte growth and to inhibit tube formation of endothelial cells. This protein is also an angiogenesis inhibitor. Genetic variation in this gene is associated with a risk for type 2 diabetes, central obesity and serum levels of systemic immune mediators in a body size-dependent manner. This gene is also a candidate gene for age-related macular degeneration, though a direct link has yet to be demonstrated. [provided by RefSeq, Sep 2009].

Function:
May be an angiogenesis inhibitor.

Subcellular Location:
Membrane; Single-pass type II membrane protein.

Similarity:
Belongs to the chondromodulin-1 family.
Contains 1 BRICHOS domain.

SWISS:
Q9H2S6

Gene ID:
64102

Database links:

Entrez Gene: 64102 Human

Entrez Gene: 64103 Mouse

Entrez Gene: 64104 Rat

Omim: 300459 Human

SwissProt: Q9H2S6 Human

SwissProt: Q9EP64 Mouse

SwissProt: Q9ESC2 Rat

Unigene: 132957 Human

Unigene: 46221 Mouse

Unigene: 26691 Rat



产品图片
Sample:
Lane 1: Muscle (Rat) Lysate at 40 ug
Lane 2: HepG2 (Human) Cell Lysate at 30 ug
Lane 3: Heart (Rat) Lysate at 40 ug
Lane 4: SW480 (Human) Cell Lysate at 30 ug
Primary: Anti- TNMD (bs-41215R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 37 kD
Observed band size: 35 kD
Sample:
Lane 1: Skeletal muscle (Rat) Lysate at 40 ug
Lane 2: Skeletal muscle (Mouse) Lysate at 40 ug
Primary: Anti-TNMD (bs-41215R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 37 kD
Observed band size: 37 kD
Paraformaldehyde-fixed, paraffin embedded (rat heart); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (TNMD) Polyclonal Antibody, Unconjugated (bs-41215R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
Paraformaldehyde-fixed, paraffin embedded (rat heart); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (TNMD) Polyclonal Antibody, Unconjugated (bs-41215R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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