产品编号 | D50449 |
英文名称 | 2,3-DCPE hydrochloride |
中文名称 | 2,3-DCPE盐酸盐 |
别 名 | 2,3-DCPE; |
克 隆 号 | |
CAS | 418788-90-6 |
理论分子量 | kDa |
检测分子量 | |
保存条件 | Store at -20℃. |
注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
产品介绍 |
CAS号:418788-90-6 分子式:C11H15Cl2NO2.HCl 分子量:300.61 纯度:99%(HPLC) 熔点:139-142℃ 沸点:429.8℃ at 760 mmHg 溶解性:Soluble in water (>25 mg/ml), ethanol (~20 mg/ml), DMSO (~20 mg/ml), DMF (~20 mg/ml), and PBS (pH7.2) (~10 mg/ml). 产品描述:2,3 DCPE displays anticancer agent properties and induces ERK activation. Causes apoptosis in many tumor cell lines and is known to specifically cleave caspase-8, caspase-3, caspase-9, and poly(ADP-ribose) polymerase in cancer cells, but not in human fibroblasts. Shown to reduce the protein level of Bcl-XL. Triggered cell death in OAW42-R ovarian carcinoma cells with inhibition of Bcl-2 expression and increased cytotoxic effect of cisplatin in OAW42-R resistant cells. 2,3-DCPE reported to induce S-phase arrest and upregulate p21. IC50:LoVo colon cancer cell line: IC50 = 0.89 µM (human); normal fibroblasts: IC50 = 12.6 µM (human) 用途:A compound that induces both upregulation and S-phase arrest in p21. |
1、抗体溶解方法 | |
2、抗体修复方式 | |
3、常用试剂的配制 | |
4、免疫组化操作步骤 | |
5、免疫组化问题解答 | |
6、Western Blotting 操作步骤 | |
7、Western Blotting 问题解答 | |
8、关于肽链的设计 | |
9、多肽的溶解与保存 | |
10、酶标抗体效价测定程序 | |