| 产品编号 |
bs-41250P |
| 英文名称 |
Recombinant human NLRP3 protein, His
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| 中文名称 |
重组人NALP3蛋白 |
| 别 名 |
LRR and PYD domains-containing protein 3; AGTAVPRL; AII/AVP antibody Angiotensin/vasopressin receptor AII/AVP like; Angiotensin/vasopressin receptor AII/AVP-like; C1orf7; Caterpiller protein 1.1; CIAS 1; CIAS1; CLR1.1; Cold autoinflammatory syndrome 1; Cold autoinflammatory syndrome 1 protein; Cryopyrin; Familial cold autoinflammatory syndrome; FCAS; FCU; Muckle-Wells syndrome; MWS; NACHT; NACHT LRR and PYD containing protein 3; NALP 3; NALP3_HUMAN; PYPAF 1; PYPAF1 antibody PYRIN containing APAF1 like protein 1; PYRIN-containing APAF1-like protein 1; Recombinant human NLRP3 protein, His |
| 克 隆 号 |
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| 理论分子量 |
25.8 kDa |
| 检测分子量 |
34 |
| 性 状 |
Liquid |
| 浓 度 |
＞0.5 mg/ml |
| 物 种 |
Human |
| 序 列 |
4-223/1036 |
| 纯 度 |
>90% as determined by SDS-PAGE |
| 纯化方法 |
AC |
| 内毒素 |
Not analyzed |
| 表达系统 |
E.coli |
| 活性 |
Not tested |
| 标签 |
His |
| 缓 冲 液 |
20mM Tris-HCl (pH9.0) with 10% Glycerol. |
| 保存条件 |
Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
| 注意事项 |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 |
May function as an inducer of apoptosis. Interacts selectively with ASC and this complex may function as an upstream activator of NF-kappa-B signaling. Inhibits TNF-alpha induced activation and nuclear translocation of RELA/NF-KB p65. Also inhibits transcriptional activity of RELA. Activates caspase-1 in response to a number of triggers including bacterial or viral infection which leads to processing and release of IL1B and IL18. Subcellular Location : Cytoplasm.
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| 产品图片 |
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.
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