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产品中心-北京博奥森生物技术有限公司
Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD (N501Y), His (bs-46011P)
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100ug/3980.00元
500ug/12500.00元
1mg/38000.00元
大包装/询价
产品编号 bs-46011P
英文名称 Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD (N501Y), His
中文名称 重组SARS冠状病毒2 Spike突变蛋白RBD(N501Y) (His Tag)
别    名 SARS-CoV-2 spike protein; 2019-nCOV Spike protein; Spike glycoprotein; Spike protein S1; Surface glycoprotein; Spike protein RBD; SPIKE_SARS2; 2019-nCOV Spike protein(N501Y), Recombinant (His Tag); Recombinant SARS-COV-2 S protein RBD (N501Y) Protein.   
分 子 量 26.2kDa
性    状 Lyophilized or Liquid
种属同源 SARS-CoV-2
序    列 Arg319 - Phe541 (N501Y) .
产品来源 基因工程表达
分    类 重组蛋白
纯化方法 亲和层析
产品应用 Immunology research 
保存条件 Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
产品介绍 The ongoing coronavirus disease 2019 (COVID-19) pandemic has prioritized the development of small-animal models for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The resulting mouse-adapted strain at passage 6 (called MASCp6) showed increased infectivity in mouse lung and led to interstitial pneumonia and inflammatory responses in both young and aged mice after intranasal inoculation. Deep sequencing revealed a panel of adaptive mutations potentially associated with the increased virulence. In particular, the N501Y mutation is located at the receptor binding domain (RBD) of the spike protein.

SWISS:
P0DTC2

Gene ID:
43740568

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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