| 产品编号 | bsm-51698M |
| 英文名称 | FOLR2 |
| 中文名称 | 胎盘叶酸受体蛋白2单克隆抗体 |
| 别 名 | Folate receptor beta; fetal/placental; Folbp 2; beta hFR; FBP; FBP/PL 1; FBP2; folate receptor 2 (fetal); Folate receptor 2; Folate receptor; Folate receptor, fetal/placental; Folbp2; FOLR2_HUMAN; FR beta; FR P3; FR-beta; Placental folate binding protein; Placental folate-binding protein. |
| 研究领域 | 细胞生物 新陈代谢 |
| 抗体来源 | Mouse |
| 克隆类型 | Monoclonal |
| 克 隆 号 | F4E5 |
| 交叉反应 | Human |
| 产品应用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 25kDa |
| 细胞定位 | 细胞膜 分泌型蛋白 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | Recombinant human FOLR2. |
| 亚 型 | IgG2b,κ |
| 纯化方法 | affinity purified by Protein G |
| 缓 冲 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
The protein encoded by this gene is a member of the folate receptor (FOLR) family, and these genes exist in a cluster on chromosome 11. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and they mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This protein has a 68% and 79% sequence homology with the FOLR1 and FOLR3 proteins, respectively. Although this protein was originally thought to be specific to placenta, it can also exist in other tissues, and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients. Multiple transcript variants that encode the same protein have been found for this gene. [provided by RefSeq, Jul 2008] Function: Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate to the interior of cells. Subcellular Location: Cell membrane. Secreted. Tissue Specificity: Expressed in placenta and hematopoietic cells. Expression is increased in malignant tissues. Post-translational modifications: Eight disulfide bonds are present. N-glycosylated. Similarity: Belongs to the folate receptor family. SWISS: P14207 Gene ID: 2350 Database links: Entrez Gene: 2350 Human SwissProt: P14207 Human |
| 产品图片 |
Sample:
Lane 1: Human spleen tissue lysates Lane 2: Human placenta tissue lysates Primary: Anti-FOLR2 (bsm-51698M) at 1/1000~2000 dilution Secondary: IRDye800CW Goat Anti-Mouse IgG at 1/20000 dilution Predicted band size: 25 kD Observed band size: 30 kD |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
