| 产品编号 |
bs-43036P |
| 英文名称 |
Recombinant human SIGLEC15 protein, His (HEK293)
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| 中文名称 |
重组人唾液酸结合性免疫球蛋白样凝集素15 |
| 别 名 |
CD33 antigen-like 3; CD33 molecule-like 3; CD33L3; HsT1361; Sialic acid-binding Ig-like lectin 15; SIG15_HUMAN; Siglec-15; SIGLEC15; Recombinant human SIGLEC15 protein, His (HEK293) |
| 克 隆 号 |
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| 理论分子量 |
30 kDa |
| 检测分子量 |
34 |
| 性 状 |
Lyophilized or Liquid |
| 浓 度 |
＞0.5 mg/ml |
| 物 种 |
Human |
| 序 列 |
20-263/328 |
| 纯 度 |
>95% as determined by SDS-PAGE |
| 纯化方法 |
AC |
| 内毒素 |
Not analyzed |
| 表达系统 |
HEK293 cell |
| 活性 |
Yes |
| 标签 |
His |
| 缓 冲 液 |
PBS (pH7.4). |
| 保存条件 |
Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
| 注意事项 |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 |
Two families of mammalian lectin-like adhesion molecules, the selectins and the sialoadhesins, bind glycoconjugate ligands in a sialic acid-dependent manner. The sialic acid-binding immunoglobulin superfamily lectins, designated Siglecs or sialoadhesins, recognize sialylated ligands and play a key role in mediating sialic-acid dependent binding to cells. Siglec-15 (sialic acid binding Ig-like lectin 15), also known as CD33L3, is a 328 amino acid single-pass type I membrane protein that contains one Ig-like C2-type domain and one Ig-like V-type domain. Expressed in dendritic and macrophage cells, Sinlec-15 interacts with DAP10 and DAP12 and binds to sialylated glycoproteins. The gene encoding Siglec-15 maps to human chromosome 18, which houses over 300 protein-coding genes and contains nearly 76 million bases.
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| 产品图片 |
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.
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