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产品中心-北京博奥森生物技术有限公司
Recombinant Chinese cobra Cytotoxin 1 protein, His (bs-49194P)
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说明书: 100ug  
100ug/3980.00元
大包装/询价

产品编号 bs-49194P
英文名称 Recombinant Chinese cobra Cytotoxin 1 protein, His
中文名称 重组眼镜蛇蛇毒蛋白
别    名 3SA1_NAJAT; Cytotoxin 1 · Naja atra (Chinese cobra); Cytotoxin1; Recombinant Chinese cobra Cytotoxin 1 protein, His  
理论分子量 22.2kDa
检测分子量 27 kDa
性    状 Lyophilized or Liquid
浓    度 >0.5 mg/ml
物    种 Cobra
序    列 22-81/81
纯    度 >95% as determined by SDS-PAGE
纯化方法 AC
内毒素 Not analyzed
表达系统 E.coli
活性 Not tested
标签 His
缓 冲 液 20 mM Tris-HCl (pH=8.0) with 0.25 mM NaCl
保存条件 Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 Basic protein that binds to cell membrane and depolarizes cardiomyocytes. It also shows lytic activities on many other cells, including red blood cells. Interaction with sulfatides in the cell membrane induces pore formation and cell internalization and is responsible for cytotoxicity in cardiomyocytes. It targets the mitochondrial membrane and induces mitochondrial swelling and fragmentation (By similarity). It binds to the integrin alpha-V/beta-3 (ITGAV/ITGB3) with a moderate affinity and inhibits protein kinases C (PubMed:8448165). It also binds with high affinity to heparin (PubMed:17685633).

SWISS:
P60304

Gene ID:
N/A

产品图片
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.
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