产品编号 |
bs-41380P |
英文名称 |
Recombinant human Bcl-6 protein, N-Sumo
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中文名称 |
重组人原癌基因Bcl-6蛋白 |
别 名 |
Bcl-6/5; Bcl-6+Bcl-5; B-cell lymphoma 6 protein isoform 1; zinc finger transcription factor BCL6S; B-cell lymphoma 6 protein transcript; BCL-5; BCL6; Bcl 6; protein LAZ-3; B-cell lymphoma 5 protein; zinc finger and BTB domain-containing protein 27; lymphoma-associated zinc finger gene on chromosome 3; zinc finger protein 51; cys-his2 zinc finger transcription factor; BCL5; BCL6A; LAZ3; ZBTB27; ZNF51; BCL6_HUMAN; Recombinant human Bcl-6 protein, N-Sumo |
克 隆 号 |
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理论分子量 |
70 kDa |
检测分子量 |
70 |
性 状 |
Lyophilized or Liquid |
浓 度 |
>0.5 mg/ml |
物 种 |
Human |
序 列 |
183-706/706 |
纯 度 |
>90% as determined by SDS-PAGE |
纯化方法 |
AC |
内毒素 |
Not analyzed |
表达系统 |
E.coli |
活性 |
Not tested |
标签 |
N-Sumo |
缓 冲 液 |
PBS (pH7.4). |
保存条件 |
Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
注意事项 |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
产品介绍 |
The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of START-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq].
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产品图片 |
The purity of the protein is greater than 68% as determined by reducing SDS-PAGE.
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