| 产品编号 |
bs-43104P |
| 英文名称 |
Recombinant human TIE2 protein, C-hFc & His (HEK293)
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| 中文名称 |
重组人血管生成素受体2蛋白 |
| 别 名 |
Tie-2; Tie2; Tek; Angiopoietin-1 receptor; Tyrosine-protein kinase receptor TIE-2; hTIE2; Tyrosine-protein kinase receptor TEK; Tunica interna endothelial cell kinase; p140 TEK; Angiopoietin 1 receptor; CD202b; CD202b antigen; Endothelial tyrosine kinase; Endothelium specific receptor tyrosine kinase 2; hTIE 2; Hyk; Soluble TIE2 variant 1; Soluble TIE2 variant 2; tek tyrosine kinase; TEK tyrosine kinase endothelial; tek tyrosine kinase, endothelial; TIE 2; TIE2_HUMAN; Tunica interna endothelial cell kinase; Tyrosine kinase with Ig and EGF homology domains 2; Tyrosine protein kinase receptor TEK; Tyrosine protein kinase receptor TIE 2; Tyrosine-protein kinase receptor TIE-2; Venous malformations multiple cutaneous and mucosal; VMCM 1; VMCM; VMCM1; CD202b; Recombinant human TIE2 protein, C-hFc & His (HEK293) |
| 克 隆 号 |
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| 理论分子量 |
108 kDa |
| 检测分子量 |
130-140 |
| 性 状 |
Lyophilized or Liquid |
| 浓 度 |
＞0.5 mg/ml |
| 物 种 |
Human |
| 序 列 |
23-745/1124 |
| 纯 度 |
>90% as determined by SDS-PAGE |
| 纯化方法 |
AC |
| 内毒素 |
Not analyzed |
| 表达系统 |
HEK293 cell |
| 活性 |
Not tested |
| 标签 |
C-hFc & His |
| 缓 冲 液 |
10 mM TBS (pH=7.4). |
| 保存条件 |
Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
| 注意事项 |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 |
The TEK receptor tyrosine kinase is expressed almost exclusively in endothelial cells in mice, rats, and humans. This receptor possesses a unique extracellular domain containing 2 immunoglobulin-like loops separated by 3 epidermal growth factor-like repeats that are connected to 3 fibronectin type III-like repeats. The ligand for the receptor is angiopoietin-1. Defects in TEK are associated with inherited venous malformations; the TEK signaling pathway appears to be critical for endothelial cell-smooth muscle cell communication in venous morphogenesis.TEK is closely related to the TIE receptor tyrosine kinase.
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| 产品图片 |
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.
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