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产品中心-北京博奥森生物技术有限公司
Recombinant human IL-21 protein (Active, HEK293) (bs-48033P)
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说明书: 10ug  50ug  500ug
10ug/2080.00元
50ug/6800.00元
500ug/28000.00元
大包装/询价
产品编号 bs-48033P
英文名称 Recombinant human IL-21 protein (Active, HEK293)
中文名称 重组人白介素-21(活性的)
别    名 Human IL-21;IL-21;h-IL-21;rh-IL-21;recombinant human IL-21;recombinant IL-21;IL;interluekin;Recombinant human IL-21 protein (Active, HEK293)  
检测分子量 15 kDa
性    状 Lyophilized powder
浓    度 >0.5 mg/ml
物    种 Human
序    列 1-132/162
纯    度 >95% as determined by SDS-PAGE
纯化方法 AC
内毒素 <0.5 EU/μg as determined by LAL.
表达系统 HEK293 cell
活性 Yes
标签 Tag free
保存条件 Use a manual defrost freezer and avoid repeated freeze-thaw cycles. In general: 12 months from date of receipt, -20 to -80℃ as supplied. 1 month, 2 to 8℃ under sterile conditions after reconstitution. 3 months, -20 to -80℃ under sterile conditions after reconstitution.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 IL-21 is a typical family I cytokine with broad pleiotropic actions and is primarily produced by T follicular helper cells, Th17, and natural killer T cells in response to antigenic stimulation. Il-21 generally enhances antigen-specific responses of immune cells. It controls the activation, proliferation, differentiation, cytotoxicity, and survival of various target immune cells. Additionally, IL-21 promotes the anti-tumor activity of CD8+ T-cells and NK cells. IL-21 elicits its effect through binding to IL-21R, which also contains the gamma chain found in other cytokine receptors such as IL-2, IL-4, IL-7, IL-9 and IL-15. IL-21/IL-21R interaction triggers a cascade of events, which includes activation of the tyrosine kinases JAK1 and JAK3, followed by activation of the transcription factors STAT1 and STAT3. Recombinant Human IL-21 is a 15.4 kDa protein consisting of 132 amino acid residues.

SWISS:
Q9HBE4

Gene ID:
59067

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