| 产品编号 |
bs-48035P |
| 英文名称 |
Recombinant human NGF-β protein (Active, HEK293)
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| 中文名称 |
重组人神经生长因子（活性的） |
| 别 名 |
Beta-NGF Protein, Human；HSAN5 Protein, Human； NGFB Protein, Human；Recombinant human Nerve growth factor;Recombinant human NGF-β protein (Active, HEK293) |
| 克 隆 号 |
|
| 理论分子量 |
kDa |
| 检测分子量 |
25 |
| 性 状 |
Lyophilized |
| 浓 度 |
＞0.5 mg/ml |
| 物 种 |
Human |
| 序 列 |
1-241/241 |
| 纯 度 |
>95% as determined by SDS-PAGE |
| 纯化方法 |
AC |
| 内毒素 |
<0.5 EU/μg as determined by LAL. |
| 表达系统 |
HEK293 cell |
| 活性 |
Yes |
| 标签 |
Tag free |
| 保存条件 |
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. In general: 12 months from date of receipt, -20 to -80℃ as supplied. 1 month, 2 to 8℃ under sterile conditions after reconstitution. 3 months, -20 to -80℃ under sterile conditions after r |
| 注意事项 |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 |
Nerve growth factor (NGF) is important for the development and maintenance of the sympathetic and sensory nervous systems. NGF protein was identified as a large complex consisting of three non-covalently linked subunits, α, β, and γ, among which, the β subunit, called β-NGF (beta-NGF), was demonstrated to exhibits the growth-stimulating activity of NGF protein. NGFB/beta-NGF gene is a member of the NGF-beta family and encodes a secreted protein that homodimerizes and is incorporated into a larger complex. NGF protein acts via at least two receptors on the surface of cells (TrkA and p75 receptors) to regulate neuronal survival, promote neurite outgrowth, and up-regulate certain neuronal functions such as mediation of pain and inflammation. Also, previous studies indicated that NGF may also have an important role in the regulation of the immune system.
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